Cohen FE - Search Results

1

Chalcone, acyl hydrazide, and related amides kill cultured Trypanosoma brucei brucei.

Troeberg L, Chen X, Flaherty TM, Morty RE, Cheng M, Hua H, Springer C, McKerrow JH, Kenyon GL, Lonsdale-Eccles JD, Coetzer TH, Cohen FE. Troeberg L, et al. Among authors: cohen fe. Mol Med. 2000 Aug;6(8):660-9. Mol Med. 2000. PMID: 11055585 Free PMC article.

2

Screening of acyl hydrazide proteinase inhibitors for antiparasitic activity against Trypanosoma brucei.

Caffrey CR, Schanz M, Nkemngu NJ, Brush M, Hansell E, Cohen FE, Flaherty TM, McKerrow JH, Steverding D. Caffrey CR, et al. Among authors: cohen fe. Int J Antimicrob Agents. 2002 Mar;19(3):227-31. doi: 10.1016/s0924-8579(01)00488-5. Int J Antimicrob Agents. 2002. PMID: 11932146

3

Aryl ureas represent a new class of anti-trypanosomal agents.

Du X, Hansell E, Engel JC, Caffrey CR, Cohen FE, McKerrow JH. Du X, et al. Among authors: cohen fe. Chem Biol. 2000 Sep;7(9):733-42. doi: 10.1016/s1074-5521(00)00018-1. Chem Biol. 2000. PMID: 10980453

4

Synthesis and structure-activity relationship study of potent trypanocidal thio semicarbazone inhibitors of the trypanosomal cysteine protease cruzain.

Du X, Guo C, Hansell E, Doyle PS, Caffrey CR, Holler TP, McKerrow JH, Cohen FE. Du X, et al. Among authors: cohen fe. J Med Chem. 2002 Jun 20;45(13):2695-707. doi: 10.1021/jm010459j. J Med Chem. 2002. PMID: 12061873

5

Leishmania major: molecular modeling of cysteine proteases and prediction of new nonpeptide inhibitors.

Selzer PM, Chen X, Chan VJ, Cheng M, Kenyon GL, Kuntz ID, Sakanari JA, Cohen FE, McKerrow JH. Selzer PM, et al. Among authors: cohen fe. Exp Parasitol. 1997 Nov;87(3):212-21. doi: 10.1006/expr.1997.4220. Exp Parasitol. 1997. PMID: 9371086

6

CoMFA and HQSAR of acylhydrazide cruzain inhibitors.

Rodrigues CR, Flaherty TM, Springer C, McKerrow JH, Cohen FE. Rodrigues CR, et al. Among authors: cohen fe. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1537-41. doi: 10.1016/s0960-894x(02)00189-0. Bioorg Med Chem Lett. 2002. PMID: 12031337

7

Structure-based design of parasitic protease inhibitors.

Li R, Chen X, Gong B, Selzer PM, Li Z, Davidson E, Kurzban G, Miller RE, Nuzum EO, McKerrow JH, Fletterick RJ, Gillmor SA, Craik CS, Kuntz ID, Cohen FE, Kenyon GL. Li R, et al. Among authors: cohen fe. Bioorg Med Chem. 1996 Sep;4(9):1421-7. doi: 10.1016/0968-0896(96)00136-8. Bioorg Med Chem. 1996. PMID: 8894100 Free article.

8

Helix-helix packing angle preferences for finite helix axes.

Walther D, Springer C, Cohen FE. Walther D, et al. Among authors: cohen fe. Proteins. 1998 Dec 1;33(4):457-9. Proteins. 1998. PMID: 9849932

9

In vitro antimalarial activity of chalcones and their derivatives.

Li R, Kenyon GL, Cohen FE, Chen X, Gong B, Dominguez JN, Davidson E, Kurzban G, Miller RE, Nuzum EO, et al. Li R, et al. Among authors: cohen fe. J Med Chem. 1995 Dec 22;38(26):5031-7. doi: 10.1021/jm00026a010. J Med Chem. 1995. PMID: 8544179

10

Characterization of a Plasmodium vivax cysteine proteinase gene identifies uniquely conserved amino acids that may mediate the substrate specificity of malarial hemoglobinases.

Rosenthal PJ, Ring CS, Chen X, Cohen FE. Rosenthal PJ, et al. Among authors: cohen fe. J Mol Biol. 1994 Aug 12;241(2):312-6. doi: 10.1006/jmbi.1994.1506. J Mol Biol. 1994. PMID: 8057374

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