Ife RJ - Search Results

1

Diastereoselective synthesis, activity and chiral stability of cyclic alkoxyketone inhibitors of cathepsin K.

Fenwick AE, Gribble AD, Ife RJ, Stevens N, Witherington J. Fenwick AE, et al. Among authors: ife rj. Bioorg Med Chem Lett. 2001 Jan 22;11(2):199-202. doi: 10.1016/s0960-894x(00)00627-2. Bioorg Med Chem Lett. 2001. PMID: 11206458

2

SB-656104-A: a novel 5-HT(7) receptor antagonist with improved in vivo properties.

Forbes IT, Douglas S, Gribble AD, Ife RJ, Lightfoot AP, Garner AE, Riley GJ, Jeffrey P, Stevens AJ, Stean TO, Thomas DR. Forbes IT, et al. Among authors: ife rj. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3341-4. doi: 10.1016/s0960-894x(02)00690-x. Bioorg Med Chem Lett. 2002. PMID: 12392747

3

5-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Garland SL, Hickey DM, Ife RJ, Liddle J, Saunders M, Smith DG, Ward RW. Witherington J, et al. Among authors: ife rj. Bioorg Med Chem Lett. 2003 May 5;13(9):1577-80. doi: 10.1016/s0960-894x(03)00134-3. Bioorg Med Chem Lett. 2003. PMID: 12699759

4

5-aryl-pyrazolo[3,4-b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Haigh D, Hickey DM, Ife RJ, Rawlings AD, Slingsby BP, Smith DG, Ward RW. Witherington J, et al. Among authors: ife rj. Bioorg Med Chem Lett. 2003 May 5;13(9):1581-4. doi: 10.1016/s0960-894x(03)00135-5. Bioorg Med Chem Lett. 2003. PMID: 12699760

5

ATP-Citrate lyase as a target for hypolipidemic intervention. 2. Synthesis and evaluation of (3R,5S)-omega-substituted-3-carboxy-3, 5-dihydroxyalkanoic acids and their gamma-lactone prodrugs as inhibitors of the enzyme in vitro and in vivo.

Gribble AD, Ife RJ, Shaw A, McNair D, Novelli CE, Bakewell S, Shah VP, Dolle RE, Groot PH, Pearce N, Yates J, Tew D, Boyd H, Ashman S, Eggleston DS, Haltiwanger RC, Okafo G. Gribble AD, et al. Among authors: ife rj. J Med Chem. 1998 Sep 10;41(19):3582-95. doi: 10.1021/jm980091z. J Med Chem. 1998. PMID: 9733484

6

The inhibition of human cytomegalovirus (hCMV) protease by hydroxylamine derivatives.

Smith DG, Gribble AD, Haigh D, Ife RJ, Lavery P, Skett P, Slingsby BP, Stacey R, Ward RW, West A. Smith DG, et al. Among authors: ife rj. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3137-42. doi: 10.1016/s0960-894x(99)00539-9. Bioorg Med Chem Lett. 1999. PMID: 10560740

7

Solid-phase synthesis of cyclic alkoxyketones, inhibitors of the cysteine protease cathepsin K.

Fenwick AE, Garnier B, Gribble AD, Ife RJ, Rawlings AD, Witherington J. Fenwick AE, et al. Among authors: ife rj. Bioorg Med Chem Lett. 2001 Jan 22;11(2):195-8. doi: 10.1016/s0960-894x(00)00626-0. Bioorg Med Chem Lett. 2001. PMID: 11206457

8

3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

Smith DG, Buffet M, Fenwick AE, Haigh D, Ife RJ, Saunders M, Slingsby BP, Stacey R, Ward RW. Smith DG, et al. Among authors: ife rj. Bioorg Med Chem Lett. 2001 Mar 12;11(5):635-9. doi: 10.1016/s0960-894x(00)00721-6. Bioorg Med Chem Lett. 2001. PMID: 11266159

9

Conformationally restricted indolopiperidine derivatives as potent CCR2B receptor antagonists.

Witherington J, Bordas V, Cooper DG, Forbes IT, Gribble AD, Ife RJ, Berkhout T, Gohil J, Groot PH. Witherington J, et al. Among authors: ife rj. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2177-80. doi: 10.1016/s0960-894x(01)00397-3. Bioorg Med Chem Lett. 2001. PMID: 11514164

10

Identification of a novel series of selective 5-HT7 receptor antagonists.

Forbes IT, Cooper DG, Dodds EK, Douglas SE, Gribble AD, Ife RJ, Lightfoot AP, Meeson M, Campbell LP, Coleman T, Riley GJ, Thomas DR. Forbes IT, et al. Among authors: ife rj. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1055-8. doi: 10.1016/s0960-894x(03)00077-5. Bioorg Med Chem Lett. 2003. PMID: 12643910

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