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Malignant glioma cells use MHC class II transactivator (CIITA) promoters III and IV to direct IFN-gamma-inducible CIITA expression and can function as nonprofessional antigen presenting cells in endocytic processing and CD4(+) T-cell activation.
Soos JM, Krieger JI, Stüve O, King CL, Patarroyo JC, Aldape K, Wosik K, Slavin AJ, Nelson PA, Antel JP, Zamvil SS. Soos JM, et al. Among authors: stuve o. Glia. 2001 Dec;36(3):391-405. doi: 10.1002/glia.1125. Glia. 2001. PMID: 11746775
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