Activating and inactivating mutations in N- and C-terminal i3 loop junctions of muscarinic acetylcholine Hm1 receptors.
Högger P, Shockley MS, Lameh J, Sadée W.
Högger P, et al.
J Biol Chem. 1995 Mar 31;270(13):7405-10. doi: 10.1074/jbc.270.13.7405.
J Biol Chem. 1995.
PMID: 7706286
Free article.
We had previously constructed two triple point alanine mutants of the i3 junction of the muscarinic Hm1 receptor, W209A/I211A/Y212A and E360A/K362A/T366A, which are defective in mediating carbachol stimulation of phosphatidylinositol (PI) turnover (Moro, O., Lameh, J., Hogger …
We had previously constructed two triple point alanine mutants of the i3 junction of the muscarinic Hm1 receptor, W209A/I211A/Y212A and E360 …