Prendergast K - Search Results

1

Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1).

Nantermet PG, Barrow JC, Lundell GF, Pellicore JM, Rittle KE, Young M, Freidinger RM, Connolly TM, Condra C, Karczewski J, Bednar RA, Gaul SL, Gould RJ, Prendergast K, Selnick HG. Nantermet PG, et al. Among authors: prendergast k. Bioorg Med Chem Lett. 2002 Feb 11;12(3):319-23. doi: 10.1016/s0960-894x(01)00745-4. Bioorg Med Chem Lett. 2002. PMID: 11814787

2

Potent 3-spiropiperidine growth hormone secretagogues.

Yang L, Morriello G, Prendergast K, Cheng K, Jacks T, Chan WW, Schleim KD, Smith RG, Patchett AA. Yang L, et al. Among authors: prendergast k. Bioorg Med Chem Lett. 1998 Jan 6;8(1):107-12. doi: 10.1016/s0960-894x(97)10199-8. Bioorg Med Chem Lett. 1998. PMID: 9925440

3

Tripeptide growth hormone secretagogues.

Yang L, Morriello G, Pan Y, Nargund RP, Barakat K, Prendergast K, Cheng K, Chan WW, Smith RG, Patchett AA. Yang L, et al. Among authors: prendergast k. Bioorg Med Chem Lett. 1998 Apr 7;8(7):759-64. doi: 10.1016/s0960-894x(98)00103-6. Bioorg Med Chem Lett. 1998. PMID: 9871537

4

Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.

Wexler RR, Greenlee WJ, Irvin JD, Goldberg MR, Prendergast K, Smith RD, Timmermans PB. Wexler RR, et al. Among authors: prendergast k. J Med Chem. 1996 Feb 2;39(3):625-56. doi: 10.1021/jm9504722. J Med Chem. 1996. PMID: 8576904 Review. No abstract available.

5

A novel 3-substituted benzazepinone growth hormone secretagogue (L-692,429).

Schoen WR, Pisano JM, Prendergast K, Wyvratt MJ Jr, Fisher MH, Cheng K, Chan WW, Butler B, Smith RG, Ball RG. Schoen WR, et al. Among authors: prendergast k. J Med Chem. 1994 Apr 1;37(7):897-906. doi: 10.1021/jm00033a006. J Med Chem. 1994. PMID: 8151616

6

Structural model of antagonist and agonist binding to the angiotensin II, AT1 subtype, G protein coupled receptor.

Underwood DJ, Strader CD, Rivero R, Patchett AA, Greenlee W, Prendergast K. Underwood DJ, et al. Among authors: prendergast k. Chem Biol. 1994 Dec;1(4):211-21. doi: 10.1016/1074-5521(94)90013-2. Chem Biol. 1994. PMID: 9383393

7

Derivation of a 3D pharmacophore model for the angiotensin-II site one receptor.

Prendergast K, Adams K, Greenlee WJ, Nachbar RB, Patchett AA, Underwood DJ. Prendergast K, et al. J Comput Aided Mol Des. 1994 Oct;8(5):491-512. doi: 10.1007/BF00123662. J Comput Aided Mol Des. 1994. PMID: 7876897

8

Getting it together: signal transduction in G-protein coupled receptors by association of receptor domains.

Underwood DJ, Prendergast K. Underwood DJ, et al. Among authors: prendergast k. Chem Biol. 1997 Apr;4(4):239-48. doi: 10.1016/s1074-5521(97)90067-3. Chem Biol. 1997. PMID: 9195871 Review.

9

A New Orphan Receptor Involved in Pulsatile Growth Hormone Release.

Smith RG, Feighner S, Prendergast K, Guan X, Howard A. Smith RG, et al. Among authors: prendergast k. Trends Endocrinol Metab. 1999 May;10(4):128-135. doi: 10.1016/s1043-2760(98)00132-5. Trends Endocrinol Metab. 1999. PMID: 10322406

10

Structural requirements for the activation of the human growth hormone secretagogue receptor by peptide and nonpeptide secretagogues.

Feighner SD, Howard AD, Prendergast K, Palyha OC, Hreniuk DL, Nargund R, Underwood D, Tata JR, Dean DC, Tan CP, McKee KK, Woods JW, Patchett AA, Smith RG, Van der Ploeg LH. Feighner SD, et al. Among authors: prendergast k. Mol Endocrinol. 1998 Jan;12(1):137-45. doi: 10.1210/mend.12.1.0051. Mol Endocrinol. 1998. PMID: 9440817

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