Cazenave JP - Search Results

1

Novel antagonists acting at the P2Y(1) purinergic receptor: synthesis and conformational analysis using potentiometric and nuclear magnetic resonance titration techniques.

Raboisson P, Baurand A, Cazenave JP, Gachet C, Retat M, Spiess B, Bourguignon JJ. Raboisson P, et al. Among authors: cazenave jp. J Med Chem. 2002 Feb 14;45(4):962-72. doi: 10.1021/jm0104062. J Med Chem. 2002. PMID: 11831909

2

A general approach toward the synthesis of C-nucleoside pyrazolo[1,5-a]-1,3,5-triazines and their 3',5'-bisphosphate C-nucleotide analogues as the first reported in vivo stable P2Y(1)-receptor antagonists.

Raboisson P, Baurand A, Cazenave JP, Gachet C, Schultz D, Spiess B, Bourguignon JJ. Raboisson P, et al. Among authors: cazenave jp. J Org Chem. 2002 Nov 15;67(23):8063-71. doi: 10.1021/jo026268l. J Org Chem. 2002. PMID: 12423133

3

Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties?

Baurand A, Eckly A, Hechler B, Kauffenstein G, Galzi JL, Cazenave JP, Léon C, Gachet C. Baurand A, et al. Among authors: cazenave jp. Mol Pharmacol. 2005 Mar;67(3):721-33. doi: 10.1124/mol.104.004846. Epub 2004 Dec 15. Mol Pharmacol. 2005. PMID: 15602005

4

Key role of the P2Y(1) receptor in tissue factor-induced thrombin-dependent acute thromboembolism: studies in P2Y(1)-knockout mice and mice treated with a P2Y(1) antagonist.

Léon C, Freund M, Ravanat C, Baurand A, Cazenave JP, Gachet C. Léon C, et al. Among authors: cazenave jp. Circulation. 2001 Feb 6;103(5):718-23. doi: 10.1161/01.cir.103.5.718. Circulation. 2001. PMID: 11156884

5

Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist.

Baurand A, Raboisson P, Freund M, Léon C, Cazenave JP, Bourguignon JJ, Gachet C. Baurand A, et al. Among authors: cazenave jp. Eur J Pharmacol. 2001 Feb 2;412(3):213-21. doi: 10.1016/s0014-2999(01)00733-6. Eur J Pharmacol. 2001. PMID: 11166284

6

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice.

Léon C, Hechler B, Freund M, Eckly A, Vial C, Ohlmann P, Dierich A, LeMeur M, Cazenave JP, Gachet C. Léon C, et al. Among authors: cazenave jp. J Clin Invest. 1999 Dec;104(12):1731-7. doi: 10.1172/JCI8399. J Clin Invest. 1999. PMID: 10606627 Free PMC article.

7

Desensitization of the platelet aggregation response to ADP: differential down-regulation of the P2Y1 and P2cyc receptors.

Baurand A, Eckly A, Bari N, Léon C, Hechler B, Cazenave JP, Gachet C. Baurand A, et al. Among authors: cazenave jp. Thromb Haemost. 2000 Sep;84(3):484-91. Thromb Haemost. 2000. PMID: 11019976

8

ADP induced blood platelet activation: a review.

Gachet C, Cazenave JP. Gachet C, et al. Among authors: cazenave jp. Nouv Rev Fr Hematol (1978). 1991;33(5):347-58. Nouv Rev Fr Hematol (1978). 1991. PMID: 1803325 Review.

9

Anti-platelet drugs: do they affect megakaryocytes?

Cazenave JP, Gachet C. Cazenave JP, et al. Baillieres Clin Haematol. 1997 Feb;10(1):163-80. doi: 10.1016/s0950-3536(97)80056-x. Baillieres Clin Haematol. 1997. PMID: 9154321 Review.

10

Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity.

Leon C, Ravanat C, Freund M, Cazenave JP, Gachet C. Leon C, et al. Among authors: cazenave jp. Arterioscler Thromb Vasc Biol. 2003 Oct 1;23(10):1941-7. doi: 10.1161/01.ATV.0000092127.16125.E6. Epub 2003 Aug 21. Arterioscler Thromb Vasc Biol. 2003. PMID: 12933533

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