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Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase.
Crespo RA, Dang Q, Zhou NE, Guthrie LM, Snavely TC, Dong W, Loesch KA, Suzuki T, You L, Wang W, O'Malley T, Parish T, Olsen DB, Sacchettini JC. Crespo RA, et al. Among authors: loesch ka. J Med Chem. 2019 May 9;62(9):4483-4499. doi: 10.1021/acs.jmedchem.9b00020. Epub 2019 Apr 19. J Med Chem. 2019. PMID: 31002508 Free PMC article.
Mycobacterium Cytidylate Kinase Appears to Be an Undruggable Target.
Craig JK, Risler JK, Loesch KA, Dong W, Baker D, Barrett LK, Subramanian S, Samudrala R, Van Voorhis WC. Craig JK, et al. Among authors: loesch ka. J Biomol Screen. 2016 Aug;21(7):695-700. doi: 10.1177/1087057116646702. Epub 2016 May 4. J Biomol Screen. 2016. PMID: 27146385 Free PMC article.
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