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Dual requirement for a newly identified phosphorylation site in p70s6k.
Moser BA, Dennis PB, Pullen N, Pearson RB, Williamson NA, Wettenhall RE, Kozma SC, Thomas G. Moser BA, et al. Among authors: pullen n. Mol Cell Biol. 1997 Sep;17(9):5648-55. doi: 10.1128/MCB.17.9.5648. Mol Cell Biol. 1997. PMID: 9271440 Free PMC article.
Phosphorylation and activation of p70s6k by PDK1.
Pullen N, Dennis PB, Andjelkovic M, Dufner A, Kozma SC, Hemmings BA, Thomas G. Pullen N, et al. Science. 1998 Jan 30;279(5351):707-10. doi: 10.1126/science.279.5351.707. Science. 1998. PMID: 9445476
Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation.
Dennis PB, Pullen N, Pearson RB, Kozma SC, Thomas G. Dennis PB, et al. Among authors: pullen n. J Biol Chem. 1998 Jun 12;273(24):14845-52. doi: 10.1074/jbc.273.24.14845. J Biol Chem. 1998. PMID: 9614086 Free article.
Earlier studies showed that truncation of the p70(s6k) amino terminus severely impaired kinase activation but that this effect was reversed by deleting the carboxyl terminus, which in parallel led to deregulation of Thr229 phosphorylation in the activation loop (Dennis, P. B., …
Earlier studies showed that truncation of the p70(s6k) amino terminus severely impaired kinase activation but that this effect was reversed …
115 results