Elkins JM - Search Results

1

X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates.

Elkins JM, Ryle MJ, Clifton IJ, Dunning Hotopp JC, Lloyd JS, Burzlaff NI, Baldwin JE, Hausinger RP, Roach PL. Elkins JM, et al. Biochemistry. 2002 Apr 23;41(16):5185-92. doi: 10.1021/bi016014e. Biochemistry. 2002. PMID: 11955067

2

A device for the high-pressure oxygenation of protein crystals.

Rutledge PJ, Burzlaff NI, Elkins JM, Pickford M, Baldwin JE, Roach PL. Rutledge PJ, et al. Among authors: elkins jm. Anal Biochem. 2002 Sep 15;308(2):265-8. doi: 10.1016/s0003-2697(02)00246-4. Anal Biochem. 2002. PMID: 12419338

3

Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue.

Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Elkins JM, et al. Org Biomol Chem. 2003 May 7;1(9):1455-60. doi: 10.1039/b212270g. Org Biomol Chem. 2003. PMID: 12926272

4

Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight.

Howard-Jones AR, Elkins JM, Clifton IJ, Roach PL, Adlington RM, Baldwin JE, Rutledge PJ. Howard-Jones AR, et al. Among authors: elkins jm. Biochemistry. 2007 Apr 24;46(16):4755-62. doi: 10.1021/bi062314q. Epub 2007 Mar 31. Biochemistry. 2007. PMID: 17397141

5

Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction.

Ogle JM, Clifton IJ, Rutledge PJ, Elkins JM, Burzlaff NI, Adlington RM, Roach PL, Baldwin JE. Ogle JM, et al. Among authors: elkins jm. Chem Biol. 2001 Dec;8(12):1231-7. doi: 10.1016/s1074-5521(01)00090-4. Chem Biol. 2001. PMID: 11755401

6

Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis.

Elkins JM, Clifton IJ, Hernández H, Doan LX, Robinson CV, Schofield CJ, Hewitson KS. Elkins JM, et al. Biochem J. 2002 Sep 1;366(Pt 2):423-34. doi: 10.1042/BJ20020125. Biochem J. 2002. PMID: 12020346 Free PMC article.

7

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha.

Elkins JM, Hewitson KS, McNeill LA, Seibel JF, Schlemminger I, Pugh CW, Ratcliffe PJ, Schofield CJ. Elkins JM, et al. J Biol Chem. 2003 Jan 17;278(3):1802-6. doi: 10.1074/jbc.C200644200. Epub 2002 Nov 21. J Biol Chem. 2003. PMID: 12446723 Free article.

8

The role of iron and 2-oxoglutarate oxygenases in signalling.

Hewitson KS, McNeill LA, Elkins JM, Schofield CJ. Hewitson KS, et al. Among authors: elkins jm. Biochem Soc Trans. 2003 Jun;31(Pt 3):510-5. doi: 10.1042/bst0310510. Biochem Soc Trans. 2003. PMID: 12773146 Review.

9

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.

Hewitson KS, McNeill LA, Riordan MV, Tian YM, Bullock AN, Welford RW, Elkins JM, Oldham NJ, Bhattacharya S, Gleadle JM, Ratcliffe PJ, Pugh CW, Schofield CJ. Hewitson KS, et al. Among authors: elkins jm. J Biol Chem. 2002 Jul 19;277(29):26351-5. doi: 10.1074/jbc.C200273200. Epub 2002 May 31. J Biol Chem. 2002. PMID: 12042299 Free article.

10

Crystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathway.

Caines ME, Elkins JM, Hewitson KS, Schofield CJ. Caines ME, et al. Among authors: elkins jm. J Biol Chem. 2004 Feb 13;279(7):5685-92. doi: 10.1074/jbc.M310803200. Epub 2003 Nov 17. J Biol Chem. 2004. PMID: 14623876 Free article.

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