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Page 1
N-Aroyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Lou JP, Chen L, Kaplan G, Mennona F, Campbell R, Guthrie R, Huang TN, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Among authors: lou jp. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2479-82. doi: 10.1016/s0960-894x(02)00387-6. Bioorg Med Chem Lett. 2002. PMID: 12161162
Identification of N-acyl 4-(5-pyrimidine-2,4-dionyl)phenylalanine derivatives and their orally active prodrug esters as dual-acting alpha4-beta1 and alpha4-beta7 receptor antagonists.
Sidduri A, Tilley JW, Lou J, Tare N, Cavallo G, Frank K, Pamidimukkala A, Choi DS, Gerber L, Railkar A, Renzetti L. Sidduri A, et al. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1026-31. doi: 10.1016/j.bmcl.2012.12.026. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23312474
N-Cycloalkanoyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Hull K, Lou JP, Kaplan G, Sheffron A, Chen L, Campbell R, Guthrie R, Huang TN, Huby N, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Among authors: lou jp. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2475-8. doi: 10.1016/s0960-894x(02)00386-4. Bioorg Med Chem Lett. 2002. PMID: 12161161
2,3-Disubstituted acrylamides as potent glucokinase activators.
Sidduri A, Grimsby JS, Corbett WL, Sarabu R, Grippo JF, Lou J, Kester RF, Dvorozniak M, Marcus L, Spence C, Racha JK, Moore DJ. Sidduri A, et al. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5673-6. doi: 10.1016/j.bmcl.2010.08.029. Epub 2010 Aug 11. Bioorg Med Chem Lett. 2010. PMID: 20805029
Synthesis and activity of quinolinyl-methylene-thiazolinones as potent and selective cyclin-dependent kinase 1 inhibitors.
Chen S, Chen L, Le NT, Zhao C, Sidduri A, Lou JP, Michoud C, Portland L, Jackson N, Liu JJ, Konzelmann F, Chi F, Tovar C, Xiang Q, Chen Y, Wen Y, Vassilev LT. Chen S, et al. Among authors: lou jp. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2134-8. doi: 10.1016/j.bmcl.2007.01.081. Epub 2007 Jan 31. Bioorg Med Chem Lett. 2007. PMID: 17303421
Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1.
Goodnow RA Jr, Hicks A, Sidduri A, Kowalczyk A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Tilley J, Cohen N, Choudhry S, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Tare NS, Oh H, Lamb M, Kurylko G, Hamid R, Wright MB, Pamidimukkala A, Egan T, Gubler U, Hoffman AF, Wei X, Li YL, O'Neil J, Marcano R, Pozzani K, Molinaro T, Santiago J, Singer L, Hargaden M, Moore D, Catala AR, Chao LC, Hermann G, Venkat R, Mancebo H, Renzetti LM. Goodnow RA Jr, et al. Among authors: lou jp. J Med Chem. 2010 May 13;53(9):3502-16. doi: 10.1021/jm1001919. J Med Chem. 2010. PMID: 20380377
Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates.
Hicks A, Goodnow R Jr, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Lora JM, Satjawatcharaphong J, Brovarney M, Dabbagh K, Tare NS, Oh H, Lamb M, Sidduri A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Kowalczyk A, Kurylko G, Hamid R, Wright MB, Pamidimukkala A, Egan T, Gubler U, Hoffman AF, Wei X, Li YL, O'Neil J, Marcano R, Pozzani K, Molinaro T, Santiago J, Singer L, Hargaden M, Moore D, Catala AR, Chao LC, Benson J, March T, Venkat R, Mancebo H, Renzetti LM. Hicks A, et al. Among authors: lou jp. Prostaglandins Other Lipid Mediat. 2010 Jun;92(1-4):33-43. doi: 10.1016/j.prostaglandins.2010.02.003. Epub 2010 Mar 7. Prostaglandins Other Lipid Mediat. 2010. PMID: 20214997
14 results