McHugh PJ - Search Results

1

Saccharomyces cerevisiae RAD5 influences the excision repair of DNA minor groove adducts.

Kiakos K, Howard TT, Lee M, Hartley JA, McHugh PJ. Kiakos K, et al. Among authors: mchugh pj. J Biol Chem. 2002 Nov 15;277(46):44576-81. doi: 10.1074/jbc.M208169200. Epub 2002 Sep 10. J Biol Chem. 2002. PMID: 12226100 Free article.

2

DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase.

Barber LJ, Ward TA, Hartley JA, McHugh PJ. Barber LJ, et al. Among authors: mchugh pj. Mol Cell Biol. 2005 Mar;25(6):2297-309. doi: 10.1128/MCB.25.6.2297-2309.2005. Mol Cell Biol. 2005. PMID: 15743825 Free PMC article.

3

DNA sequence selective adenine alkylation, mechanism of adduct repair, and in vivo antitumor activity of the novel achiral seco-amino-cyclopropylbenz[e]indolone analogue of duocarmycin AS-I-145.

Kiakos K, Sato A, Asao T, McHugh PJ, Lee M, Hartley JA. Kiakos K, et al. Among authors: mchugh pj. Mol Cancer Ther. 2007 Oct;6(10):2708-18. doi: 10.1158/1535-7163.MCT-07-0294. Mol Cancer Ther. 2007. PMID: 17938264

4

Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases.

Sengerová B, Allerston CK, Abu M, Lee SY, Hartley J, Kiakos K, Schofield CJ, Hartley JA, Gileadi O, McHugh PJ. Sengerová B, et al. Among authors: mchugh pj. J Biol Chem. 2012 Jul 27;287(31):26254-67. doi: 10.1074/jbc.M112.367243. Epub 2012 Jun 11. J Biol Chem. 2012. PMID: 22692201 Free PMC article.

5

Excision repair of nitrogen mustard-DNA adducts in Saccharomyces cerevisiae.

McHugh PJ, Gill RD, Waters R, Hartley JA. McHugh PJ, et al. Nucleic Acids Res. 1999 Aug 15;27(16):3259-66. doi: 10.1093/nar/27.16.3259. Nucleic Acids Res. 1999. PMID: 10454632 Free PMC article.

6

Repair of intermediate structures produced at DNA interstrand cross-links in Saccharomyces cerevisiae.

McHugh PJ, Sones WR, Hartley JA. McHugh PJ, et al. Mol Cell Biol. 2000 May;20(10):3425-33. doi: 10.1128/MCB.20.10.3425-3433.2000. Mol Cell Biol. 2000. PMID: 10779332 Free PMC article.

7

Alteration in the choice of DNA repair pathway with increasing sequence selective DNA alkylation in the minor groove.

Brooks N, McHugh PJ, Lee M, Hartley JA. Brooks N, et al. Among authors: mchugh pj. Chem Biol. 2000 Sep;7(9):659-68. doi: 10.1016/s1074-5521(00)00010-7. Chem Biol. 2000. PMID: 10980446

8

Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to cisplatin.

De Silva IU, McHugh PJ, Clingen PH, Hartley JA. De Silva IU, et al. Among authors: mchugh pj. Nucleic Acids Res. 2002 Sep 1;30(17):3848-56. doi: 10.1093/nar/gkf479. Nucleic Acids Res. 2002. PMID: 12202770 Free PMC article.

9

The XPF-ERCC1 endonuclease and homologous recombination contribute to the repair of minor groove DNA interstrand crosslinks in mammalian cells produced by the pyrrolo[2,1-c][1,4]benzodiazepine dimer SJG-136.

Clingen PH, De Silva IU, McHugh PJ, Ghadessy FJ, Tilby MJ, Thurston DE, Hartley JA. Clingen PH, et al. Among authors: mchugh pj. Nucleic Acids Res. 2005 Jun 8;33(10):3283-91. doi: 10.1093/nar/gki639. Print 2005. Nucleic Acids Res. 2005. PMID: 15944449 Free PMC article.

10

Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants.

Hazrati A, Ramis-Castelltort M, Sarkar S, Barber LJ, Schofield CJ, Hartley JA, McHugh PJ. Hazrati A, et al. Among authors: mchugh pj. DNA Repair (Amst). 2008 Feb 1;7(2):230-8. doi: 10.1016/j.dnarep.2007.09.013. Epub 2007 Nov 19. DNA Repair (Amst). 2008. PMID: 18006388

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