Clements CS - Search Results

1

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state.

Clements CS, Kjer-Nielsen L, MacDonald WA, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Clements CS, et al. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2131-4. doi: 10.1107/s0907444902015482. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454477

2

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: clements cs. Structure. 2002 Nov;10(11):1521-32. doi: 10.1016/s0969-2126(02)00878-x. Structure. 2002. PMID: 12429093 Free article.

3

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition.

Borg NA, Ely LK, Beddoe T, Macdonald WA, Reid HH, Clements CS, Purcell AW, Kjer-Nielsen L, Miles JJ, Burrows SR, McCluskey J, Rossjohn J. Borg NA, et al. Among authors: clements cs. Nat Immunol. 2005 Feb;6(2):171-80. doi: 10.1038/ni1155. Epub 2005 Jan 9. Nat Immunol. 2005. PMID: 15640805

4

The production, purification and crystallization of a soluble form of the nonclassical MHC HLA-G: the essential role of cobalt.

Clements CS, Kjer-Nielsen L, Kostenko L, McCluskey J, Rossjohn J. Clements CS, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jan 1;62(Pt 1):70-3. doi: 10.1107/S1744309105041473. Epub 2005 Dec 16. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16511266 Free PMC article.

5

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction.

Ely LK, Beddoe T, Clements CS, Matthews JM, Purcell AW, Kjer-Nielsen L, McCluskey J, Rossjohn J. Ely LK, et al. Among authors: clements cs. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6641-6. doi: 10.1073/pnas.0600743103. Epub 2006 Apr 14. Proc Natl Acad Sci U S A. 2006. PMID: 16617112 Free PMC article.

6

Specificity on a knife-edge: the alphabeta T cell receptor.

Clements CS, Dunstone MA, Macdonald WA, McCluskey J, Rossjohn J. Clements CS, et al. Curr Opin Struct Biol. 2006 Dec;16(6):787-95. doi: 10.1016/j.sbi.2006.09.004. Epub 2006 Sep 29. Curr Opin Struct Biol. 2006. PMID: 17011774 Review.

7

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.

Archbold JK, Macdonald WA, Gras S, Ely LK, Miles JJ, Bell MJ, Brennan RM, Beddoe T, Wilce MC, Clements CS, Purcell AW, McCluskey J, Burrows SR, Rossjohn J. Archbold JK, et al. Among authors: clements cs. J Exp Med. 2009 Jan 16;206(1):209-19. doi: 10.1084/jem.20082136. Epub 2009 Jan 12. J Exp Med. 2009. PMID: 19139173 Free PMC article.

8

The shaping of T cell receptor recognition by self-tolerance.

Gras S, Burrows SR, Kjer-Nielsen L, Clements CS, Liu YC, Sullivan LC, Bell MJ, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Gras S, et al. Among authors: clements cs. Immunity. 2009 Feb 20;30(2):193-203. doi: 10.1016/j.immuni.2008.11.011. Epub 2009 Jan 22. Immunity. 2009. PMID: 19167249 Free article.

9

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex.

Macdonald W, Williams DS, Clements CS, Gorman JJ, Kjer-Nielsen L, Brooks AG, McCluskey J, Rossjohn J, Purcell AW. Macdonald W, et al. Among authors: clements cs. FEBS Lett. 2002 Sep 11;527(1-3):27-32. doi: 10.1016/s0014-5793(02)03149-6. FEBS Lett. 2002. PMID: 12220628 Free article.

10

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, Fontes MR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: clements cs. J Immunol. 2002 Nov 1;169(9):5153-60. doi: 10.4049/jimmunol.169.9.5153. J Immunol. 2002. PMID: 12391232

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