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HMGB1 as a DNA-binding cytokine.
Andersson U, Erlandsson-Harris H, Yang H, Tracey KJ. Andersson U, et al. J Leukoc Biol. 2002 Dec;72(6):1084-91. J Leukoc Biol. 2002. PMID: 12488489 Review.
HMGB1 is a potent trigger of arthritis.
Andersson U, Erlandsson-Harris H. Andersson U, et al. J Intern Med. 2004 Mar;255(3):344-50. doi: 10.1111/j.1365-2796.2003.01303.x. J Intern Med. 2004. PMID: 14871458 Free article. Review.
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release.
Yang H, Hreggvidsdottir HS, Palmblad K, Wang H, Ochani M, Li J, Lu B, Chavan S, Rosas-Ballina M, Al-Abed Y, Akira S, Bierhaus A, Erlandsson-Harris H, Andersson U, Tracey KJ. Yang H, et al. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11942-7. doi: 10.1073/pnas.1003893107. Epub 2010 Jun 14. Proc Natl Acad Sci U S A. 2010. PMID: 20547845 Free PMC article.
54 results