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Studies of chemical selectivity of hapten, reactivity, and skin sensitization potency. 3. Synthesis and studies on the reactivity toward model nucleophiles of the 13C-labeled skin sensitizers, 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisothiazol-3-one (MI).
Alvarez-Sánchez R, Basketter D, Pease C, Lepoittevin JP. Alvarez-Sánchez R, et al. Among authors: lepoittevin jp. Chem Res Toxicol. 2003 May;16(5):627-36. doi: 10.1021/tx0256634. Chem Res Toxicol. 2003. PMID: 12755592
Effect of glutathione on the covalent binding of the 13C-labeled skin sensitizer 5-chloro-2-methylisothiazol-3-one to human serum albumin: identification of adducts by nuclear magnetic resonance, matrix-assisted laser desorption/ionization mass spectrometry, and nanoelectrospray tandem mass spectrometry.
Alvarez-Sánchez R, Divkovic M, Basketter D, Pease C, Panico M, Dell A, Morris H, Lepoittevin JP. Alvarez-Sánchez R, et al. Among authors: lepoittevin jp. Chem Res Toxicol. 2004 Sep;17(9):1280-8. doi: 10.1021/tx049935+. Chem Res Toxicol. 2004. PMID: 15377163
144 results