Boot JR - Search Results

1

Bicyclo[2.2.1]heptanes as novel triple re-uptake inhibitors for the treatment of depression.

Axford L, Boot JR, Hotten TM, Keenan M, Martin FM, Milutinovic S, Moore NA, O'Neill MF, Pullar IA, Tupper DE, Van Belle KR, Vivien V. Axford L, et al. Among authors: boot jr. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3277-80. doi: 10.1016/s0960-894x(03)00660-7. Bioorg Med Chem Lett. 2003. PMID: 12951108

2

High affinity ligands for the alpha7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor.

Baker SR, Boot J, Brunavs M, Dobson D, Green R, Hayhurst L, Keenan M, Wallace L. Baker SR, et al. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4727-30. doi: 10.1016/j.bmcl.2005.07.070. Bioorg Med Chem Lett. 2005. PMID: 16165358

3

SAR development of a selective 5-HT1D antagonist/serotonin reuptake inhibitor lead using rapid parallel synthesis.

Timms GH, Boot JR, Broadmore RJ, Carney SL, Cooper J, Findlay JD, Gilmore J, Mitchell S, Moore NA, Pullar I, Sanger GJ, Tomlinson R, Tree BB, Wedley S. Timms GH, et al. Among authors: boot jr. Bioorg Med Chem Lett. 2004 May 17;14(10):2469-72. doi: 10.1016/j.bmcl.2004.03.003. Bioorg Med Chem Lett. 2004. PMID: 15109634

4

Recent progress in the development of subtype selective nicotinic acetylcholine receptor ligands.

Astles PC, Baker SR, Boot JR, Broad LM, Dell CP, Keenan M. Astles PC, et al. Among authors: boot jr. Curr Drug Targets CNS Neurol Disord. 2002 Aug;1(4):337-48. doi: 10.2174/1568007023339256. Curr Drug Targets CNS Neurol Disord. 2002. PMID: 12769608 Review.

5

Discovery and structure-activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors.

Boot J, Cases M, Clark BP, Findlay J, Gallagher PT, Hayhurst L, Man T, Montalbetti C, Rathmell RE, Rudyk H, Walter MW, Whatton M, Wood V. Boot J, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):699-703. doi: 10.1016/j.bmcl.2004.11.025. Bioorg Med Chem Lett. 2005. PMID: 15664840

6

1-Aryl-3,4-dihydro-1H-quinolin-2-one derivatives, novel and selective norepinephrine reuptake inhibitors.

Beadle CD, Boot J, Camp NP, Dezutter N, Findlay J, Hayhurst L, Masters JJ, Penariol R, Walter MW. Beadle CD, et al. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4432-7. doi: 10.1016/j.bmcl.2005.07.038. Bioorg Med Chem Lett. 2005. PMID: 16137883

7

The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig.

Pullar IA, Boot JR, Broadmore RJ, Eyre TA, Cooper J, Sanger GJ, Wedley S, Mitchell SN. Pullar IA, et al. Among authors: boot jr. Eur J Pharmacol. 2004 Jun 16;493(1-3):85-93. doi: 10.1016/j.ejphar.2004.04.029. Eur J Pharmacol. 2004. PMID: 15189767

8

N-Alkyl-N-arylmethylpiperidin-4-amines: novel dual inhibitors of serotonin and norepinephrine reuptake.

Boot JR, Boulet SL, Clark BP, Cases-Thomas MJ, Delhaye L, Diker K, Fairhurst J, Findlay J, Gallagher PT, Gilmore J, Harris JR, Masters JJ, Mitchell SN, Naik M, Simmonds RG, Smith SM, Richards SJ, Timms GH, Whatton MA, Wolfe CN, Wood VA. Boot JR, et al. Bioorg Med Chem Lett. 2006 May 15;16(10):2714-8. doi: 10.1016/j.bmcl.2006.02.008. Epub 2006 Feb 23. Bioorg Med Chem Lett. 2006. PMID: 16497500

9

Benzothienyloxy phenylpropanamines, novel dual inhibitors of serotonin and norepinephrine reuptake.

Boot JR, Brace G, Delatour CL, Dezutter N, Fairhurst J, Findlay J, Gallagher PT, Hoes I, Mahadevan S, Mitchell SN, Rathmell RE, Richards SJ, Simmonds RG, Wallace L, Whatton MA. Boot JR, et al. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5395-9. doi: 10.1016/j.bmcl.2004.08.005. Bioorg Med Chem Lett. 2004. PMID: 15454233

10

Discovery of novel and selective tertiary alcohol containing inhibitors of the norepinephrine transporter.

Cases-Thomas MJ, Masters JJ, Walter MW, Campbell G, Haughton L, Gallagher PT, Dobson DR, Mancuso V, Bonnier B, Giard T, Defrance T, Vanmarsenille M, Ledgard A, White C, Ouwerkerk-Mahadevan S, Brunelle FJ, Dezutter NA, Herbots CA, Lienard JY, Findlay J, Hayhurst L, Boot J, Thompson LK, Hemrick-Luecke S. Cases-Thomas MJ, et al. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2022-5. doi: 10.1016/j.bmcl.2005.12.061. Epub 2006 Jan 18. Bioorg Med Chem Lett. 2006. PMID: 16413778

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