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A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives.
Sullivan V, Biron KK, Talarico C, Stanat SC, Davis M, Pozzi LM, Coen DM. Sullivan V, et al. Among authors: davis m. Antimicrob Agents Chemother. 1993 Jan;37(1):19-25. doi: 10.1128/AAC.37.1.19. Antimicrob Agents Chemother. 1993. PMID: 8381637 Free PMC article.
Ganciclovir-resistant mutant 759rD100 derived from human cytomegalovirus strain AD169 contains two resistance mutations, one of which is in the UL97 gene and results in decreased ganciclovir phosphorylation in infected cells [V. Sullivan, C. L. Talarico, S. C. Stanat, M. …
Ganciclovir-resistant mutant 759rD100 derived from human cytomegalovirus strain AD169 contains two resistance mutations, one of which is in …
Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein.
Talarico CL, Burnette TC, Miller WH, Smith SL, Davis MG, Stanat SC, Ng TI, He Z, Coen DM, Roizman B, Biron KK. Talarico CL, et al. Among authors: davis mg. Antimicrob Agents Chemother. 1999 Aug;43(8):1941-6. doi: 10.1128/AAC.43.8.1941. Antimicrob Agents Chemother. 1999. PMID: 10428917 Free PMC article.
Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action.
Biron KK, Harvey RJ, Chamberlain SC, Good SS, Smith AA 3rd, Davis MG, Talarico CL, Miller WH, Ferris R, Dornsife RE, Stanat SC, Drach JC, Townsend LB, Koszalka GW. Biron KK, et al. Antimicrob Agents Chemother. 2002 Aug;46(8):2365-72. doi: 10.1128/AAC.46.8.2365-2372.2002. Antimicrob Agents Chemother. 2002. PMID: 12121906 Free PMC article.
Synthesis and evaluation of a series of 2'-deoxy analogues of the antiviral agent 5,6-dichloro-2-isopropylamino-1-(beta-L-ribofuranosyl)-1H-benzimidazole (1263W94).
Chan JH, Chamberlain SD, Biron KK, Davis MG, Harvey RJ, Selleseth DW, Dornsife RE, Dark EH, Frick LW, Townsend LB, Drach JC, Koszalka GW. Chan JH, et al. Among authors: davis mg. Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):101-23. doi: 10.1080/15257770008032999. Nucleosides Nucleotides Nucleic Acids. 2000. PMID: 10772705
9,611 results