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Enzymological and mutational analysis of a complex primary hyperoxaluria type 1 phenotype involving alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting and intraperoxisomal aggregation.
Danpure CJ, Purdue PE, Fryer P, Griffiths S, Allsop J, Lumb MJ, Guttridge KM, Jennings PR, Scheinman JI, Mauer SM, et al. Danpure CJ, et al. Among authors: lumb mj. Am J Hum Genet. 1993 Aug;53(2):417-32. Am J Hum Genet. 1993. PMID: 8101040 Free PMC article.
Mammalian alanine/glyoxylate aminotransferase 1 is imported into peroxisomes via the PTS1 translocation pathway. Increased degeneracy and context specificity of the mammalian PTS1 motif and implications for the peroxisome-to-mitochondrion mistargeting of AGT in primary hyperoxaluria type 1.
Motley A, Lumb MJ, Oatey PB, Jennings PR, De Zoysa PA, Wanders RJ, Tabak HF, Danpure CJ. Motley A, et al. Among authors: lumb mj. J Cell Biol. 1995 Oct;131(1):95-109. doi: 10.1083/jcb.131.1.95. J Cell Biol. 1995. PMID: 7559790 Free PMC article.
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