Wang YD - Search Results

1

Investigation of the effect of varying the 4-anilino and 7-alkoxy groups of 3-quinolinecarbonitriles on the inhibition of Src kinase activity.

Boschelli DH, Ye F, Wu B, Wang YD, Barrios Sosa AC, Yaczko D, Powell D, Golas JM, Lucas J, Boschelli F. Boschelli DH, et al. Among authors: wang yd. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3797-800. doi: 10.1016/j.bmcl.2003.07.001. Bioorg Med Chem Lett. 2003. PMID: 14552782

2

7-Alkoxy-4-phenylamino-3-quinolinecar-bonitriles as dual inhibitors of Src and Abl kinases.

Boschelli DH, Wang YD, Johnson S, Wu B, Ye F, Barrios Sosa AC, Golas JM, Boschelli F. Boschelli DH, et al. Among authors: wang yd. J Med Chem. 2004 Mar 25;47(7):1599-601. doi: 10.1021/jm0499458. J Med Chem. 2004. PMID: 15027848

3

4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonitriles as potent Src kinase inhibitors.

Berger DM, Dutia M, Birnberg G, Powell D, Boschelli DH, Wang YD, Ravi M, Yaczko D, Golas J, Lucas J, Boschelli F. Berger DM, et al. Among authors: wang yd. J Med Chem. 2005 Sep 22;48(19):5909-20. doi: 10.1021/jm050512u. J Med Chem. 2005. PMID: 16161995

4

7-(aryl/heteroaryl-2-ylethynyl)-4-phenylamino-3-quinolinecarbonitriles as new Src kinase inhibitors: addition of water solubilizing groups.

Wu B, Barrios Sosa AC, Boschelli DH, Boschelli F, Honores EE, Golas JM, Powell DW, Wang YD. Wu B, et al. Among authors: wang yd. Bioorg Med Chem Lett. 2006 Aug 1;16(15):3993-7. doi: 10.1016/j.bmcl.2006.05.015. Epub 2006 Jun 2. Bioorg Med Chem Lett. 2006. PMID: 16735116

5

Inhibition of tumor cell proliferation by thieno[2,3-d]pyrimidin-4(1H)-one-based analogs.

Wang YD, Johnson S, Powell D, McGinnis JP, Miranda M, Rabindran SK. Wang YD, et al. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3763-6. doi: 10.1016/j.bmcl.2005.05.127. Bioorg Med Chem Lett. 2005. PMID: 16005212

6

Pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as novel antiproliferative agents: exploration of core and headpiece structure-activity relationships.

Powell D, Gopalsamy A, Wang YD, Zhang N, Miranda M, McGinnis JP, Rabindran SK. Powell D, et al. Among authors: wang yd. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1641-5. doi: 10.1016/j.bmcl.2006.12.116. Epub 2007 Jan 13. Bioorg Med Chem Lett. 2007. PMID: 17275298

7

Synthesis, SAR study and biological evaluation of novel pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as anti-proliferative agents.

Wang YD, Honores E, Wu B, Johnson S, Powell D, Miranda M, McGinnis JP, Discafani C, Rabindran SK, Cheng W, Krishnamurthy G. Wang YD, et al. Bioorg Med Chem. 2009 Mar 1;17(5):2091-100. doi: 10.1016/j.bmc.2008.12.046. Epub 2008 Dec 25. Bioorg Med Chem. 2009. PMID: 19200741

8

Osteogenic effects of a potent Src-over-Abl-selective kinase inhibitor in the mouse.

Murrills RJ, Fukayama S, Boschelli F, Matteo JJ, Owens J, Golas JM, Patel D, Lane G, Liu YB, Carter L, Jussif J, Spaulding V, Wang YD, Boschelli DH, McKew JC, Li XJ, Lockhead S, Milligan C, Kharode YP, Diesl V, Bai Y, Follettie M, Bex FJ, Komm B, Bodine PV. Murrills RJ, et al. Among authors: wang yd. J Pharmacol Exp Ther. 2012 Mar;340(3):676-87. doi: 10.1124/jpet.111.185793. Epub 2011 Dec 9. J Pharmacol Exp Ther. 2012. PMID: 22171089

9

Parallel synthesis and biological evaluation of 5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one cytotoxic agents selective for p21-deficient cells.

Jennings LD, Kincaid SL, Wang YD, Krishnamurthy G, Beyer CF, McGinnis JP, Miranda M, Discafani CM, Rabindran SK. Jennings LD, et al. Among authors: wang yd. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4731-5. doi: 10.1016/j.bmcl.2005.07.072. Bioorg Med Chem Lett. 2005. PMID: 16143523

10

Benzo[c][2,7]naphthyridines as inhibitors of PDK-1.

Kim KH, Wissner A, Floyd MB Jr, Fraser HL, Wang YD, Dushin RG, Hu Y, Olland A, Guo B, Arndt K. Kim KH, et al. Among authors: wang yd. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5225-8. doi: 10.1016/j.bmcl.2009.07.007. Epub 2009 Jul 8. Bioorg Med Chem Lett. 2009. PMID: 19628388

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