Qian S - Search Results

1

Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein.

Chen HY, Trumbauer ME, Chen AS, Weingarth DT, Adams JR, Frazier EG, Shen Z, Marsh DJ, Feighner SD, Guan XM, Ye Z, Nargund RP, Smith RG, Van der Ploeg LH, Howard AD, MacNeil DJ, Qian S. Chen HY, et al. Among authors: qian s. Endocrinology. 2004 Jun;145(6):2607-12. doi: 10.1210/en.2003-1596. Epub 2004 Feb 12. Endocrinology. 2004. PMID: 14962995

2

Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice.

Qian S, Chen H, Weingarth D, Trumbauer ME, Novi DE, Guan X, Yu H, Shen Z, Feng Y, Frazier E, Chen A, Camacho RE, Shearman LP, Gopal-Truter S, MacNeil DJ, Van der Ploeg LH, Marsh DJ. Qian S, et al. Mol Cell Biol. 2002 Jul;22(14):5027-35. doi: 10.1128/MCB.22.14.5027-5035.2002. Mol Cell Biol. 2002. PMID: 12077332 Free PMC article.

3

Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism.

Marsh DJ, Weingarth DT, Novi DE, Chen HY, Trumbauer ME, Chen AS, Guan XM, Jiang MM, Feng Y, Camacho RE, Shen Z, Frazier EG, Yu H, Metzger JM, Kuca SJ, Shearman LP, Gopal-Truter S, MacNeil DJ, Strack AM, MacIntyre DE, Van der Ploeg LH, Qian S. Marsh DJ, et al. Among authors: qian s. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3240-5. doi: 10.1073/pnas.052706899. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867747 Free PMC article.

4

Diet induction of monocyte chemoattractant protein-1 and its impact on obesity.

Chen A, Mumick S, Zhang C, Lamb J, Dai H, Weingarth D, Mudgett J, Chen H, MacNeil DJ, Reitman ML, Qian S. Chen A, et al. Among authors: qian s. Obes Res. 2005 Aug;13(8):1311-20. doi: 10.1038/oby.2005.159. Obes Res. 2005. PMID: 16129712 Free article.

5

Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.

Qian S, Jiang P, Guan XM, Singh G, Trumbauer ME, Yu H, Chen HY, Van de Ploeg LH, Zheng H. Qian S, et al. Neuron. 1998 Mar;20(3):611-7. doi: 10.1016/s0896-6273(00)80999-x. Neuron. 1998. PMID: 9539133 Free article.

6

Discovery of imidazole carboxamides as potent and selective CCK1R agonists.

Zhu C, Hansen AR, Bateman T, Chen Z, Holt TG, Hubert JA, Karanam BV, Lee SJ, Pan J, Qian S, Reddy VB, Reitman ML, Strack AM, Tong V, Weingarth DT, Wolff MS, MacNeil DJ, Weber AE, Duffy JL, Edmondson SD. Zhu C, et al. Among authors: qian s. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4393-6. doi: 10.1016/j.bmcl.2008.06.057. Epub 2008 Jun 20. Bioorg Med Chem Lett. 2008. PMID: 18614364

7

2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity.

Berger R, Zhu C, Hansen AR, Harper B, Chen Z, Holt TG, Hubert J, Lee SJ, Pan J, Qian S, Reitman ML, Strack AM, Weingarth DT, Wolff M, Macneil DJ, Weber AE, Edmondson SD. Berger R, et al. Among authors: qian s. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4833-7. doi: 10.1016/j.bmcl.2008.07.083. Epub 2008 Jul 24. Bioorg Med Chem Lett. 2008. PMID: 18684621

8

Discovery of pyrimidine carboxamides as potent and selective CCK1 receptor agonists.

Wang L, Hubert JA, Lee SJ, Pan J, Qian S, Reitman ML, Strack AM, Weingarth DT, MacNeil DJ, Weber AE, Edmondson SD. Wang L, et al. Among authors: qian s. Bioorg Med Chem Lett. 2011 May 15;21(10):2911-5. doi: 10.1016/j.bmcl.2011.03.069. Epub 2011 Mar 31. Bioorg Med Chem Lett. 2011. PMID: 21493064

9

Genome-wide expression profiling revealed peripheral effects of cannabinoid receptor 1 inverse agonists in improving insulin sensitivity and metabolic parameters.

Zhao W, Fong O, Muise ES, Thompson JR, Weingarth D, Qian S, Fong TM. Zhao W, et al. Among authors: qian s. Mol Pharmacol. 2010 Sep;78(3):350-9. doi: 10.1124/mol.110.064980. Epub 2010 Jun 7. Mol Pharmacol. 2010. PMID: 20530130

10

Deficiency in cytosolic malic enzyme does not increase acetaminophen-induced hepato-toxicity.

Qian S, Mumick S, Nizner P, Tota MR, Menetski J, Reitman ML, Macneil DJ. Qian S, et al. Basic Clin Pharmacol Toxicol. 2008 Jul;103(1):36-42. doi: 10.1111/j.1742-7843.2008.00228.x. Epub 2008 Jul 1. Basic Clin Pharmacol Toxicol. 2008. PMID: 18346052 Free article.

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