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Page 1
Molecular determinants of vanilloid sensitivity in TRPV1.
Gavva NR, Klionsky L, Qu Y, Shi L, Tamir R, Edenson S, Zhang TJ, Viswanadhan VN, Toth A, Pearce LV, Vanderah TW, Porreca F, Blumberg PM, Lile J, Sun Y, Wild K, Louis JC, Treanor JJ. Gavva NR, et al. Among authors: porreca f. J Biol Chem. 2004 May 7;279(19):20283-95. doi: 10.1074/jbc.M312577200. Epub 2004 Mar 2. J Biol Chem. 2004. PMID: 14996838 Free article.
AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties.
Gavva NR, Tamir R, Qu Y, Klionsky L, Zhang TJ, Immke D, Wang J, Zhu D, Vanderah TW, Porreca F, Doherty EM, Norman MH, Wild KD, Bannon AW, Louis JC, Treanor JJ. Gavva NR, et al. Among authors: porreca f. J Pharmacol Exp Ther. 2005 Apr;313(1):474-84. doi: 10.1124/jpet.104.079855. Epub 2004 Dec 22. J Pharmacol Exp Ther. 2005. PMID: 15615864
Spring pain research conference 2008.
Porreca F, Vanderah TW. Porreca F, et al. Brain Res Rev. 2009 Apr;60(1):1. doi: 10.1016/j.brainresrev.2008.12.022. Epub 2008 Dec 31. Brain Res Rev. 2009. PMID: 19150467 No abstract available.
TRPV1 receptor in expression of opioid-induced hyperalgesia.
Vardanyan A, Wang R, Vanderah TW, Ossipov MH, Lai J, Porreca F, King T. Vardanyan A, et al. Among authors: porreca f. J Pain. 2009 Mar;10(3):243-52. doi: 10.1016/j.jpain.2008.07.004. Epub 2008 Sep 6. J Pain. 2009. PMID: 18774343 Free PMC article.
The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.
Yamamoto T, Nair P, Jacobsen NE, Davis P, Ma SW, Navratilova E, Moye S, Lai J, Yamamura HI, Vanderah TW, Porreca F, Hruby VJ. Yamamoto T, et al. Among authors: porreca f. J Med Chem. 2008 Oct 23;51(20):6334-47. doi: 10.1021/jm800389v. Epub 2008 Sep 27. J Med Chem. 2008. PMID: 18821747 Free PMC article.
Structure-Activity Relationships of [des-Arg7]Dynorphin A Analogues at the κ Opioid Receptor.
Ramos-Colon CN, Lee YS, Remesic M, Hall SM, LaVigne J, Davis P, Sandweiss AJ, McIntosh MI, Hanson J, Largent-Milnes TM, Vanderah TW, Streicher J, Porreca F, Hruby VJ. Ramos-Colon CN, et al. Among authors: porreca f. J Med Chem. 2016 Nov 23;59(22):10291-10298. doi: 10.1021/acs.jmedchem.6b01411. Epub 2016 Nov 8. J Med Chem. 2016. PMID: 27797517 Free PMC article.
Development of potent μ and δ opioid agonists with high lipophilicity.
Lee YS, Kulkarani V, Cowell SM, Ma SW, Davis P, Hanlon KE, Vanderah TW, Lai J, Porreca F, Vardanyan R, Hruby VJ. Lee YS, et al. Among authors: porreca f. J Med Chem. 2011 Jan 13;54(1):382-6. doi: 10.1021/jm100982d. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128594 Free PMC article.
Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.
Yamamoto T, Nair P, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Vanderah TW, Yamamura HI, Porreca F, Hruby VJ. Yamamoto T, et al. Among authors: porreca f. J Med Chem. 2007 Jun 14;50(12):2779-86. doi: 10.1021/jm061369n. Epub 2007 May 22. J Med Chem. 2007. PMID: 17516639 Free PMC article.
Effect of anchoring 4-anilidopiperidines to opioid peptides.
Petrov RR, Lee YS, Vardanyan RS, Liu L, Ma SW, Davis P, Lai J, Porreca F, Vanderah TW, Hruby VJ. Petrov RR, et al. Among authors: porreca f. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3434-7. doi: 10.1016/j.bmcl.2013.03.065. Epub 2013 Apr 3. Bioorg Med Chem Lett. 2013. PMID: 23623418 Free PMC article.
631 results