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3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies.
J Med Chem. 2004 Mar 11;47(6):1351-9. doi: 10.1021/jm031036f.
J Med Chem. 2004.
PMID: 14998325
Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation.
Mai A, Massa S, Ragno R, Esposito M, Sbardella G, Nocca G, Scatena R, Jesacher F, Loidl P, Brosch G.
Mai A, et al. Among authors: jesacher f.
J Med Chem. 2002 Apr 25;45(9):1778-84. doi: 10.1021/jm011088+.
J Med Chem. 2002.
PMID: 11960489
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3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a new class of synthetic histone deacetylase inhibitors. 1. Design, synthesis, biological evaluation, and binding mode studies performed through three different docking procedures.
Mai A, Massa S, Ragno R, Cerbara I, Jesacher F, Loidl P, Brosch G.
Mai A, et al. Among authors: jesacher f.
J Med Chem. 2003 Feb 13;46(4):512-24. doi: 10.1021/jm021070e.
J Med Chem. 2003.
PMID: 12570373
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Cell cycle dependent role of HDAC1 for proliferation control through modulating ribosomal DNA transcription.
Meraner J, Lechner M, Schwarze F, Gander R, Jesacher F, Loidl P.
Meraner J, et al. Among authors: jesacher f.
Cell Biol Int. 2008 Sep;32(9):1073-80. doi: 10.1016/j.cellbi.2008.04.018. Epub 2008 May 2.
Cell Biol Int. 2008.
PMID: 18550396
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