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Ghrelin expression in islet cell tumors: augmented expression of ghrelin in a case of glucagonoma with multiple endocrine neoplasm type I.
Iwakura H, Hosoda K, Doi R, Komoto I, Nishimura H, Son C, Fujikura J, Tomita T, Takaya K, Ogawa Y, Hayashi T, Inoue G, Akamizu T, Hosoda H, Kojima M, Kangawa K, Imamura M, Nakao K. Iwakura H, et al. Among authors: takaya k. J Clin Endocrinol Metab. 2002 Nov;87(11):4885-8. doi: 10.1210/jc.2002-020882. J Clin Endocrinol Metab. 2002. PMID: 12414844
Transgenic mice overexpressing des-acyl ghrelin show small phenotype.
Ariyasu H, Takaya K, Iwakura H, Hosoda H, Akamizu T, Arai Y, Kangawa K, Nakao K. Ariyasu H, et al. Among authors: takaya k. Endocrinology. 2005 Jan;146(1):355-64. doi: 10.1210/en.2004-0629. Epub 2004 Oct 7. Endocrinology. 2005. PMID: 15471959
Ghrelin strongly stimulates growth hormone release in humans.
Takaya K, Ariyasu H, Kanamoto N, Iwakura H, Yoshimoto A, Harada M, Mori K, Komatsu Y, Usui T, Shimatsu A, Ogawa Y, Hosoda K, Akamizu T, Kojima M, Kangawa K, Nakao K. Takaya K, et al. J Clin Endocrinol Metab. 2000 Dec;85(12):4908-11. doi: 10.1210/jcem.85.12.7167. J Clin Endocrinol Metab. 2000. PMID: 11134161 Clinical Trial.
Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans.
Ariyasu H, Takaya K, Tagami T, Ogawa Y, Hosoda K, Akamizu T, Suda M, Koh T, Natsui K, Toyooka S, Shirakami G, Usui T, Shimatsu A, Doi K, Hosoda H, Kojima M, Kangawa K, Nakao K. Ariyasu H, et al. Among authors: takaya k. J Clin Endocrinol Metab. 2001 Oct;86(10):4753-8. doi: 10.1210/jcem.86.10.7885. J Clin Endocrinol Metab. 2001. PMID: 11600536
Substantial production of ghrelin by a human medullary thyroid carcinoma cell line.
Kanamoto N, Akamizu T, Hosoda H, Hataya Y, Ariyasu H, Takaya K, Hosoda K, Saijo M, Moriyama K, Shimatsu A, Kojima M, Kangawa K, Nakao K. Kanamoto N, et al. Among authors: takaya k. J Clin Endocrinol Metab. 2001 Oct;86(10):4984-90. doi: 10.1210/jcem.86.10.7891. J Clin Endocrinol Metab. 2001. PMID: 11600575
224 results