de Paula da Silva CH - Search Results

1

A molecular modeling and QSAR study of suppressors of the growth of Trypanosoma cruzi epimastigotes.

de Paula da Silva CH, Sanches SM, Taft CA. de Paula da Silva CH, et al. J Mol Graph Model. 2004 Sep;23(1):89-97. doi: 10.1016/j.jmgm.2004.03.013. J Mol Graph Model. 2004. PMID: 15331057

2

Structure- and ligand-based drug design of novel p38-alpha MAPK inhibitors in the fight against the Alzheimer's disease.

Pinsetta FR, Taft CA, de Paula da Silva CH. Pinsetta FR, et al. Among authors: de paula da silva ch. J Biomol Struct Dyn. 2014;32(7):1047-63. doi: 10.1080/07391102.2013.803441. Epub 2013 Jun 28. J Biomol Struct Dyn. 2014. PMID: 23805842

3

Novel aryl β-aminocarbonyl derivatives as inhibitors of Trypanosoma cruzi trypanothione reductase: binding mode revised by docking and GRIND2-based 3D-QSAR procedures.

de Paula da Silva CH, Bernardes LS, da Silva VB, Zani CL, Carvalho I. de Paula da Silva CH, et al. Among authors: da silva vb. J Biomol Struct Dyn. 2012;29(6):702-16. doi: 10.1080/07391102.2011.672633. J Biomol Struct Dyn. 2012. PMID: 22546000

4

Discovery of novel dual acetylcholinesterase inhibitors with antifibrillogenic activity related to Alzheimer's disease.

de Almeida JR, Figueiro M, Almeida WP, de Paula da Silva CHT. de Almeida JR, et al. Among authors: de paula da silva cht. Future Med Chem. 2018 May 1;10(9):1037-1053. doi: 10.4155/fmc-2017-0201. Epub 2018 Apr 20. Future Med Chem. 2018. PMID: 29676170

5

Identification of novel αβ-tubulin modulators with antiproliferative activity directed to cancer therapy using ligand and structure-based virtual screening.

Federico LB, Silva GM, de Fraga Dias A, Figueiró F, Battastini AMO, Dos Santos CBR, Costa LT, Rosa JMC, de Paula da Silva CHT. Federico LB, et al. Among authors: de paula da silva cht. Int J Biol Macromol. 2020 Dec 15;165(Pt B):3040-3050. doi: 10.1016/j.ijbiomac.2020.10.136. Epub 2020 Oct 22. Int J Biol Macromol. 2020. PMID: 33736292

6

Design of Multitarget Natural Products Analogs with Potential Anti-Alzheimer's Activity.

de Souza FN, de Lima HB, de Souza LR, Oliveira GS, de Paula da Silva CHT, Pereira ACM, da Silva Hage-Melim LI. de Souza FN, et al. Among authors: de paula da silva cht. Curr Comput Aided Drug Des. 2022;18(2):120-149. doi: 10.2174/1573409918666220328141605. Curr Comput Aided Drug Des. 2022. PMID: 35346014

7

Alzheimer's Disease: A Review from the Pathophysiology to Diagnosis, New Perspectives for Pharmacological Treatment.

Dos Santos Picanco LC, Ozela PF, de Fatima de Brito Brito M, Pinheiro AA, Padilha EC, Braga FS, de Paula da Silva CHT, Dos Santos CBR, Rosa JMC, da Silva Hage-Melim LI. Dos Santos Picanco LC, et al. Among authors: de paula da silva cht. Curr Med Chem. 2018;25(26):3141-3159. doi: 10.2174/0929867323666161213101126. Curr Med Chem. 2018. PMID: 30191777 Review.

8

In silico Study of Acetylcholinesterase and Beta-secretase Inhibitors: Potential Multitarget Anti-Alzheimer's Agents.

da Costa DC, Teixeira HRC, Silva RC, Francischini IAG, de Paula da Silva CHT, da Silva Hage-Melim LI. da Costa DC, et al. Among authors: de paula da silva cht. Cent Nerv Syst Agents Med Chem. 2022;22(2):139-150. doi: 10.2174/1871524922666220517110606. Cent Nerv Syst Agents Med Chem. 2022. PMID: 36104859

9

Potential colchicine binding site inhibitors unraveled by virtual screening, molecular dynamics and MM/PBSA.

Federico LB, Silva GM, Gomes SQ, Francischini IAG, Barcelos MP, Dos Santos CBR, Costa LT, Campos Rosa JM, de Paula da Silva CHT. Federico LB, et al. Among authors: de paula da silva cht. Comput Biol Med. 2021 Oct;137:104817. doi: 10.1016/j.compbiomed.2021.104817. Epub 2021 Aug 28. Comput Biol Med. 2021. PMID: 34488030 Free article.

10

Cubebin and derivatives as inhibitors of mitochondrial complex I. Proposed interaction with subunit B8.

Saraiva J, Siqueira CM, de Paula da Silva CH, Barreto da Silva V, Tudella VG, Silva R, Andrade E Silva ML, Dorta DJ, Bastos JK, Uyemura SA, de Albuquerque S, Curti C. Saraiva J, et al. Among authors: silva r, de albuquerque s, de paula da silva ch. J Enzyme Inhib Med Chem. 2009 Apr;24(2):599-606. doi: 10.1080/14756360802318845. J Enzyme Inhib Med Chem. 2009. PMID: 18825534

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