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Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease.
Brar SS, Grigg C, Wilson KS, Holder WD Jr, Dreau D, Austin C, Foster M, Ghio AJ, Whorton AR, Stowell GW, Whittall LB, Whittle RR, White DP, Kennedy TP. Brar SS, et al. Among authors: ghio aj. Mol Cancer Ther. 2004 Sep;3(9):1049-60. Mol Cancer Ther. 2004. PMID: 15367699
Iron regulates xanthine oxidase activity in the lung.
Ghio AJ, Kennedy TP, Stonehuerner J, Carter JD, Skinner KA, Parks DA, Hoidal JR. Ghio AJ, et al. Am J Physiol Lung Cell Mol Physiol. 2002 Sep;283(3):L563-72. doi: 10.1152/ajplung.00413.2000. Am J Physiol Lung Cell Mol Physiol. 2002. PMID: 12169576 Free article.
Carbon monoxide promotes hypoxic pulmonary vascular remodeling.
Carraway MS, Ghio AJ, Suliman HB, Carter JD, Whorton AR, Piantadosi CA. Carraway MS, et al. Among authors: ghio aj. Am J Physiol Lung Cell Mol Physiol. 2002 Apr;282(4):L693-702. doi: 10.1152/ajplung.00211.2001. Am J Physiol Lung Cell Mol Physiol. 2002. PMID: 11880294 Free article.
311 results