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Metabolism of vitamin D by human microsomal CYP2R1.
Shinkyo R, Sakaki T, Kamakura M, Ohta M, Inouye K. Shinkyo R, et al. Among authors: sakaki t. Biochem Biophys Res Commun. 2004 Nov 5;324(1):451-7. doi: 10.1016/j.bbrc.2004.09.073. Biochem Biophys Res Commun. 2004. PMID: 15465040
Novel metabolism of 1 alpha,25-dihydroxyvitamin D3 with C24-C25 bond cleavage catalyzed by human CYP24A1.
Sawada N, Kusudo T, Sakaki T, Hatakeyama S, Hanada M, Abe D, Kamao M, Okano T, Ohta M, Inouye K. Sawada N, et al. Among authors: sakaki t. Biochemistry. 2004 Apr 20;43(15):4530-7. doi: 10.1021/bi030207f. Biochemistry. 2004. PMID: 15078099
Our previous study revealed that human CYP24A1 catalyzes a remarkable metabolism consisting of both C-23 and C-24 hydroxylation pathways that used both 25(OH)D(3) and 1alpha,25(OH)(2)D(3) as substrates, while rat CYP24A1 showed extreme predominance of the C-24 over C-23 hydroxyla …
Our previous study revealed that human CYP24A1 catalyzes a remarkable metabolism consisting of both C-23 and C-24 hydroxylation pathways tha …
703 results