Effect of modification of 6-[(aminoalkyl)amino]-7H-benzo[e]-perimidin-7-ones on their cytotoxic activity toward sensitive and multidrug resistant tumor cell lines. Synthesis and biological evaluation.
Dzieduszycka M, Martelli S, Arciemiuk M, Bontemps-Gracz MM, Kupiec A, Borowski E.
Dzieduszycka M, et al. Among authors: borowski e.
Bioorg Med Chem. 2002 Apr;10(4):1025-35. doi: 10.1016/s0968-0896(01)00358-3.
Bioorg Med Chem. 2002.
PMID: 11836111
Benzoperimidines, a novel group of antitumor anthracenedione analogues, are of interest due to their ability to overcome multidrug resistance of tumor cells (Stefanska, B., Dzieduszycka, M., Bontemps-Gracz, M. M., Borowski, E., Martelli, S., Supino, R., Pratesi, G., …
Benzoperimidines, a novel group of antitumor anthracenedione analogues, are of interest due to their ability to overcome multidrug resistanc …