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The evolution of progesterone receptor ligands.
Madauss KP, Stewart EL, Williams SP. Madauss KP, et al. Med Res Rev. 2007 May;27(3):374-400. doi: 10.1002/med.20083. Med Res Rev. 2007. PMID: 17013809 Review.
Crystallization of protein-ligand complexes.
Hassell AM, An G, Bledsoe RK, Bynum JM, Carter HL 3rd, Deng SJ, Gampe RT, Grisard TE, Madauss KP, Nolte RT, Rocque WJ, Wang L, Weaver KL, Williams SP, Wisely GB, Xu R, Shewchuk LM. Hassell AM, et al. Among authors: madauss kp. Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):72-9. doi: 10.1107/S0907444906047020. Epub 2006 Dec 13. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 17164529 Free PMC article. Review.
Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists.
Washburn DG, Hoang TH, Frazee JS, Johnson L, Hammond M, Manns S, Madauss KP, Williams SP, Duraiswami C, Tran TB, Stewart EL, Grygielko ET, Glace LE, Trizna W, Nagilla R, Bray JD, Thompson SK. Washburn DG, et al. Among authors: madauss kp. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4664-8. doi: 10.1016/j.bmcl.2009.06.081. Epub 2009 Jun 25. Bioorg Med Chem Lett. 2009. PMID: 19616429
Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor.
Biggadike K, Bledsoe RK, Coe DM, Cooper TW, House D, Iannone MA, Macdonald SJ, Madauss KP, McLay IM, Shipley TJ, Taylor SJ, Tran TB, Uings IJ, Weller V, Williams SP. Biggadike K, et al. Among authors: madauss kp. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18114-9. doi: 10.1073/pnas.0909125106. Epub 2009 Oct 12. Proc Natl Acad Sci U S A. 2009. PMID: 19822747 Free PMC article.
33 results