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Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene-expression-based survival prediction.
Bea S, Zettl A, Wright G, Salaverria I, Jehn P, Moreno V, Burek C, Ott G, Puig X, Yang L, Lopez-Guillermo A, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, Gascoyne RD, Connors JM, Grogan TM, Braziel R, Fisher RI, Smeland EB, Kvaloy S, Holte H, Delabie J, Simon R, Powell J, Wilson WH, Jaffe ES, Montserrat E, Muller-Hermelink HK, Staudt LM, Campo E, Rosenwald A; Lymphoma/Leukemia Molecular Profiling Project. Bea S, et al. Blood. 2005 Nov 1;106(9):3183-90. doi: 10.1182/blood-2005-04-1399. Epub 2005 Jul 26. Blood. 2005. PMID: 16046532 Free PMC article.
Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma.
Iqbal J, Greiner TC, Patel K, Dave BJ, Smith L, Ji J, Wright G, Sanger WG, Pickering DL, Jain S, Horsman DE, Shen Y, Fu K, Weisenburger DD, Hans CP, Campo E, Gascoyne RD, Rosenwald A, Jaffe ES, Delabie J, Rimsza L, Ott G, Müller-Hermelink HK, Connors JM, Vose JM, McKeithan T, Staudt LM, Chan WC; Leukemia/Lymphoma Molecular Profiling Project. Iqbal J, et al. Leukemia. 2007 Nov;21(11):2332-43. doi: 10.1038/sj.leu.2404856. Epub 2007 Jul 12. Leukemia. 2007. PMID: 17625604 Free PMC article.
Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature.
Salaverria I, Zettl A, Beà S, Moreno V, Valls J, Hartmann E, Ott G, Wright G, Lopez-Guillermo A, Chan WC, Weisenburger DD, Gascoyne RD, Grogan TM, Delabie J, Jaffe ES, Montserrat E, Muller-Hermelink HK, Staudt LM, Rosenwald A, Campo E. Salaverria I, et al. J Clin Oncol. 2007 Apr 1;25(10):1216-22. doi: 10.1200/JCO.2006.08.4251. Epub 2007 Feb 12. J Clin Oncol. 2007. PMID: 17296973 Free PMC article.
Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma.
Salaverria I, Zettl A, Beà S, Hartmann EM, Dave SS, Wright GW, Boerma EJ, Kluin PM, Ott G, Chan WC, Weisenburger DD, Lopez-Guillermo A, Gascoyne RD, Delabie J, Rimsza LM, Braziel RM, Jaffe ES, Staudt LM, Müller-Hermelink HK, Campo E, Rosenwald A; Leukemia and Lymphoma Molecular Profiling Project (LLMPP). Salaverria I, et al. Haematologica. 2008 Sep;93(9):1327-34. doi: 10.3324/haematol.13071. Epub 2008 Aug 12. Haematologica. 2008. PMID: 18698080 Free PMC article.
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways.
Lenz G, Wright GW, Emre NC, Kohlhammer H, Dave SS, Davis RE, Carty S, Lam LT, Shaffer AL, Xiao W, Powell J, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Campo E, Jaffe ES, Delabie J, Smeland EB, Rimsza LM, Fisher RI, Weisenburger DD, Chan WC, Staudt LM. Lenz G, et al. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13520-5. doi: 10.1073/pnas.0804295105. Epub 2008 Sep 2. Proc Natl Acad Sci U S A. 2008. PMID: 18765795 Free PMC article.
644 results