Grewal IS - Search Results

1

Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40.

Law CL, Gordon KA, Collier J, Klussman K, McEarchern JA, Cerveny CG, Mixan BJ, Lee WP, Lin Z, Valdez P, Wahl AF, Grewal IS. Law CL, et al. Among authors: grewal is. Cancer Res. 2005 Sep 15;65(18):8331-8. doi: 10.1158/0008-5472.CAN-05-0095. Cancer Res. 2005. PMID: 16166310

2

Macrophages and Fc-receptor interactions contribute to the antitumour activities of the anti-CD40 antibody SGN-40.

Oflazoglu E, Stone IJ, Brown L, Gordon KA, van Rooijen N, Jonas M, Law CL, Grewal IS, Gerber HP. Oflazoglu E, et al. Among authors: grewal is. Br J Cancer. 2009 Jan 13;100(1):113-7. doi: 10.1038/sj.bjc.6604812. Epub 2008 Dec 9. Br J Cancer. 2009. PMID: 19066610 Free PMC article.

3

Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities.

McEarchern JA, Oflazoglu E, Francisco L, McDonagh CF, Gordon KA, Stone I, Klussman K, Turcott E, van Rooijen N, Carter P, Grewal IS, Wahl AF, Law CL. McEarchern JA, et al. Among authors: grewal is. Blood. 2007 Feb 1;109(3):1185-92. doi: 10.1182/blood-2006-07-034017. Epub 2006 Oct 12. Blood. 2007. PMID: 17038522 Free article.

4

Macrophages contribute to the antitumor activity of the anti-CD30 antibody SGN-30.

Oflazoglu E, Stone IJ, Gordon KA, Grewal IS, van Rooijen N, Law CL, Gerber HP. Oflazoglu E, et al. Among authors: grewal is. Blood. 2007 Dec 15;110(13):4370-2. doi: 10.1182/blood-2007-06-097014. Epub 2007 Oct 1. Blood. 2007. PMID: 17909075 Free article.

5

Potent anticarcinoma activity of the humanized anti-CD70 antibody h1F6 conjugated to the tubulin inhibitor auristatin via an uncleavable linker.

Oflazoglu E, Stone IJ, Gordon K, Wood CG, Repasky EA, Grewal IS, Law CL, Gerber HP. Oflazoglu E, et al. Among authors: grewal is. Clin Cancer Res. 2008 Oct 1;14(19):6171-80. doi: 10.1158/1078-0432.CCR-08-0916. Epub 2008 Sep 22. Clin Cancer Res. 2008. PMID: 18809969

6

Preclinical characterization of SGN-70, a humanized antibody directed against CD70.

McEarchern JA, Smith LM, McDonagh CF, Klussman K, Gordon KA, Morris-Tilden CA, Duniho S, Ryan M, Boursalian TE, Carter PJ, Grewal IS, Law CL. McEarchern JA, et al. Among authors: grewal is. Clin Cancer Res. 2008 Dec 1;14(23):7763-72. doi: 10.1158/1078-0432.CCR-08-0493. Clin Cancer Res. 2008. PMID: 19047103

7

Therapeutic interventions targeting CD40L (CD154) and CD40: the opportunities and challenges.

Law CL, Grewal IS. Law CL, et al. Among authors: grewal is. Adv Exp Med Biol. 2009;647:8-36. doi: 10.1007/978-0-387-89520-8_2. Adv Exp Med Biol. 2009. PMID: 19760064 Review.

8

Distinct apoptotic signaling characteristics of the anti-CD40 monoclonal antibody dacetuzumab and rituximab produce enhanced antitumor activity in non-Hodgkin lymphoma.

Lewis TS, McCormick RS, Emmerton K, Lau JT, Yu SF, McEarchern JA, Grewal IS, Law CL. Lewis TS, et al. Among authors: grewal is. Clin Cancer Res. 2011 Jul 15;17(14):4672-81. doi: 10.1158/1078-0432.CCR-11-0479. Epub 2011 May 24. Clin Cancer Res. 2011. PMID: 21610152

9

Novel antibody-based therapeutic agents targeting CD70: a potential approach for treating Waldenström's macroglobulinemia.

Law CL, McEarchern JA, Grewal IS. Law CL, et al. Among authors: grewal is. Clin Lymphoma Myeloma. 2009 Mar;9(1):90-3. doi: 10.3816/CLM.2009.n.024. Clin Lymphoma Myeloma. 2009. PMID: 19362984 Review.

10

Blocking of CD27-CD70 pathway by anti-CD70 antibody ameliorates joint disease in murine collagen-induced arthritis.

Oflazoglu E, Boursalian TE, Zeng W, Edwards AC, Duniho S, McEarchern JA, Law CL, Gerber HP, Grewal IS. Oflazoglu E, et al. Among authors: grewal is. J Immunol. 2009 Sep 15;183(6):3770-7. doi: 10.4049/jimmunol.0901637. Epub 2009 Aug 26. J Immunol. 2009. PMID: 19710474

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