Mangan PR - Search Results

1

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages.

Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT. Harrington LE, et al. Among authors: mangan pr. Nat Immunol. 2005 Nov;6(11):1123-32. doi: 10.1038/ni1254. Epub 2005 Oct 2. Nat Immunol. 2005. PMID: 16200070 Free article.

2

Expanding the effector CD4 T-cell repertoire: the Th17 lineage.

Harrington LE, Mangan PR, Weaver CT. Harrington LE, et al. Among authors: mangan pr. Curr Opin Immunol. 2006 Jun;18(3):349-56. doi: 10.1016/j.coi.2006.03.017. Epub 2006 Apr 17. Curr Opin Immunol. 2006. PMID: 16616472 Review.

3

Transforming growth factor-beta induces development of the T(H)17 lineage.

Mangan PR, Harrington LE, O'Quinn DB, Helms WS, Bullard DC, Elson CO, Hatton RD, Wahl SM, Schoeb TR, Weaver CT. Mangan PR, et al. Nature. 2006 May 11;441(7090):231-4. doi: 10.1038/nature04754. Epub 2006 Apr 30. Nature. 2006. PMID: 16648837

4

Th17: an effector CD4 T cell lineage with regulatory T cell ties.

Weaver CT, Harrington LE, Mangan PR, Gavrieli M, Murphy KM. Weaver CT, et al. Among authors: mangan pr. Immunity. 2006 Jun;24(6):677-688. doi: 10.1016/j.immuni.2006.06.002. Immunity. 2006. PMID: 16782025 Free article. Review.

5

IL-17 family cytokines and the expanding diversity of effector T cell lineages.

Weaver CT, Hatton RD, Mangan PR, Harrington LE. Weaver CT, et al. Among authors: mangan pr. Annu Rev Immunol. 2007;25:821-52. doi: 10.1146/annurev.immunol.25.022106.141557. Annu Rev Immunol. 2007. PMID: 17201677 Review.

6

Both Th1 and Th2 cells require P-selectin glycoprotein ligand-1 for optimal rolling on inflamed endothelium.

Mangan PR, O'Quinn D, Harrington L, Bonder CS, Kubes P, Kucik DF, Bullard DC, Weaver CT. Mangan PR, et al. Am J Pathol. 2005 Dec;167(6):1661-75. doi: 10.1016/S0002-9440(10)61249-7. Am J Pathol. 2005. PMID: 16314478 Free PMC article.

7

P-selectin can support both Th1 and Th2 lymphocyte rolling in the intestinal microvasculature.

Bonder CS, Norman MU, Macrae T, Mangan PR, Weaver CT, Bullard DC, McCafferty DM, Kubes P. Bonder CS, et al. Among authors: mangan pr. Am J Pathol. 2005 Dec;167(6):1647-60. doi: 10.1016/S0002-9440(10)61248-5. Am J Pathol. 2005. PMID: 16314477 Free PMC article.

8

Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus.

Xie JH, Zhang Y, Loubeau M, Mangan P, Heimrich E, Tovar C, Zhou X, Madia P, Doyle M, Dudhgaonkar S, Rudra A, Subramani S, Young J, Salter-Cid L, Malek TR, Struthers M. Xie JH, et al. J Immunol. 2021 Jul 1;207(1):34-43. doi: 10.4049/jimmunol.2100078. Epub 2021 Jun 9. J Immunol. 2021. PMID: 34108258

9

Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity.

Mangan PR, Su LJ, Jenny V, Tatum AL, Picarillo C, Skala S, Ditto N, Lin Z, Yang X, Cotter PZ, Shuster DJ, Song Y, Borowski V, Thomas RL, Heimrich EM, Devaux B, Das Gupta R, Carvajal I, McIntyre KW, Xie J, Zhao Q, Struthers M, Salter-Cid LM. Mangan PR, et al. J Pharmacol Exp Ther. 2015 Aug;354(2):152-65. doi: 10.1124/jpet.115.224246. Epub 2015 May 26. J Pharmacol Exp Ther. 2015. PMID: 26015463

10

Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production.

Sonnenberg GF, Mangan PR, Bezman NA, Sekiguchi DR, Luning Prak ET, Erikson J, Maltzman JS, Jordan MS, Koretzky GA. Sonnenberg GF, et al. Among authors: mangan pr. Blood. 2010 Mar 18;115(11):2186-95. doi: 10.1182/blood-2009-08-237438. Epub 2009 Dec 22. Blood. 2010. PMID: 20029045 Free PMC article.

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