Kamath AV - Search Results

1

A new chemical tool for exploring the role of the PDE4D isozyme in leukocyte function.

Chambers RJ, Abrams K, Castleberry TA, Cheng JB, Fisher DA, Kamath AV, Marfat A, Nettleton DO, Pillar JD, Salter ED, Sheils AL, Shirley JT, Turner CR, Umland JP, Lam KT. Chambers RJ, et al. Among authors: kamath av. Bioorg Med Chem Lett. 2006 Feb;16(3):718-21. doi: 10.1016/j.bmcl.2005.10.026. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16263279

2

A new chemical tool for exploring the physiological function of the PDE2 isozyme.

Chambers RJ, Abrams K, Garceau NY, Kamath AV, Manley CM, Lilley SC, Otte DA, Scott DO, Sheils AL, Tess DA, Vellekoop AS, Zhang Y, Lam KT. Chambers RJ, et al. Among authors: kamath av. Bioorg Med Chem Lett. 2006 Jan 15;16(2):307-10. doi: 10.1016/j.bmcl.2005.10.005. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275071

3

Identification of allosteric PIF-pocket ligands for PDK1 using NMR-based fragment screening and 1H-15N TROSY experiments.

Stockman BJ, Kothe M, Kohls D, Weibley L, Connolly BJ, Sheils AL, Cao Q, Cheng AC, Yang L, Kamath AV, Ding YH, Charlton ME. Stockman BJ, et al. Among authors: kamath av. Chem Biol Drug Des. 2009 Feb;73(2):179-88. doi: 10.1111/j.1747-0285.2008.00768.x. Chem Biol Drug Des. 2009. PMID: 19207420

4

Synthesis and biological activity of selective pipecolic acid-based TNF-alpha converting enzyme (TACE) inhibitors.

Letavic MA, Axt MZ, Barberia JT, Carty TJ, Danley DE, Geoghegan KF, Halim NS, Hoth LR, Kamath AV, Laird ER, Lopresti-Morrow LL, McClure KF, Mitchell PG, Natarajan V, Noe MC, Pandit J, Reeves L, Schulte GK, Snow SL, Sweeney FJ, Tan DH, Yu CH. Letavic MA, et al. Among authors: kamath av. Bioorg Med Chem Lett. 2002 May 20;12(10):1387-90. doi: 10.1016/s0960-894x(02)00183-x. Bioorg Med Chem Lett. 2002. PMID: 11992783

5

Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system.

Iffland A, Kohls D, Low S, Luan J, Zhang Y, Kothe M, Cao Q, Kamath AV, Ding YH, Ellenberger T. Iffland A, et al. Among authors: kamath av. Biochemistry. 2005 Jun 14;44(23):8312-25. doi: 10.1021/bi047313h. Biochemistry. 2005. PMID: 15938621

6

Specificity determinants of human cathepsin s revealed by crystal structures of complexes.

Pauly TA, Sulea T, Ammirati M, Sivaraman J, Danley DE, Griffor MC, Kamath AV, Wang IK, Laird ER, Seddon AP, Ménard R, Cygler M, Rath VL. Pauly TA, et al. Among authors: kamath av. Biochemistry. 2003 Mar 25;42(11):3203-13. doi: 10.1021/bi027308i. Biochemistry. 2003. PMID: 12641451

7

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.

Pauly TA, Ekstrom JL, Beebe DA, Chrunyk B, Cunningham D, Griffor M, Kamath A, Lee SE, Madura R, Mcguire D, Subashi T, Wasilko D, Watts P, Mylari BL, Oates PJ, Adams PD, Rath VL. Pauly TA, et al. Structure. 2003 Sep;11(9):1071-85. doi: 10.1016/s0969-2126(03)00167-9. Structure. 2003. PMID: 12962626 Free article.

8

Expression and protein chemistry yielding crystallization of the catalytic domain of ADAM17 complexed with a hydroxamate inhibitor.

Hoth LR, Tan DH, Wang IK, Wengender PA, Thompson MA, Kamath AV, Geoghegan KF. Hoth LR, et al. Among authors: kamath av. Protein Expr Purif. 2007 Apr;52(2):313-9. doi: 10.1016/j.pep.2006.10.021. Epub 2006 Nov 7. Protein Expr Purif. 2007. PMID: 17169570

9

Spontaneous alpha-N-6-phosphogluconoylation of a "His tag" in Escherichia coli: the cause of extra mass of 258 or 178 Da in fusion proteins.

Geoghegan KF, Dixon HB, Rosner PJ, Hoth LR, Lanzetti AJ, Borzilleri KA, Marr ES, Pezzullo LH, Martin LB, LeMotte PK, McColl AS, Kamath AV, Stroh JG. Geoghegan KF, et al. Among authors: kamath av. Anal Biochem. 1999 Feb 1;267(1):169-84. doi: 10.1006/abio.1998.2990. Anal Biochem. 1999. PMID: 9918669

10

Identification, characterization, and crystal structure of the Omega class glutathione transferases.

Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK, Danley DE, Hoth LR, Griffor MC, Kamath AV, Rosner MH, Chrunyk BA, Perregaux DE, Gabel CA, Geoghegan KF, Pandit J. Board PG, et al. Among authors: kamath av. J Biol Chem. 2000 Aug 11;275(32):24798-806. doi: 10.1074/jbc.M001706200. J Biol Chem. 2000. PMID: 10783391 Free article.

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