Nettleton DO - Search Results

1

A new chemical tool for exploring the role of the PDE4D isozyme in leukocyte function.

Chambers RJ, Abrams K, Castleberry TA, Cheng JB, Fisher DA, Kamath AV, Marfat A, Nettleton DO, Pillar JD, Salter ED, Sheils AL, Shirley JT, Turner CR, Umland JP, Lam KT. Chambers RJ, et al. Among authors: nettleton do. Bioorg Med Chem Lett. 2006 Feb;16(3):718-21. doi: 10.1016/j.bmcl.2005.10.026. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16263279

2

Fluorescently labeled analogues of dofetilide as high-affinity fluorescence polarization ligands for the human ether-a-go-go-related gene (hERG) channel.

Singleton DH, Boyd H, Steidl-Nichols JV, Deacon M, Groot MJ, Price D, Nettleton DO, Wallace NK, Troutman MD, Williams C, Boyd JG. Singleton DH, et al. Among authors: nettleton do. J Med Chem. 2007 Jun 28;50(13):2931-41. doi: 10.1021/jm0700565. Epub 2007 May 31. J Med Chem. 2007. PMID: 17536794

3

Biaryl diacid inhibitors of human s-PLA2 with anti-inflammatory activity.

Springer DM, Luh BY, Bronson JJ, McElhone KE, Mansuri MM, Gregor KR, Nettleton DO, Stanley PL, Tramposch KM. Springer DM, et al. Among authors: nettleton do. Bioorg Med Chem. 2000 May;8(5):1087-109. doi: 10.1016/s0968-0896(00)00047-x. Bioorg Med Chem. 2000. PMID: 10882020

4

Predicting safety toleration of pharmaceutical chemical leads: cytotoxicity correlations to exploratory toxicity studies.

Benbow JW, Aubrecht J, Banker MJ, Nettleton D, Aleo MD. Benbow JW, et al. Toxicol Lett. 2010 Sep 1;197(3):175-82. doi: 10.1016/j.toxlet.2010.05.016. Epub 2010 May 31. Toxicol Lett. 2010. PMID: 20576494

5

Novel inhibitor of phospholipase A2 with topical anti-inflammatory activity.

Tramposch KM, Steiner SA, Stanley PL, Nettleton DO, Franson RC, Lewin AH, Carroll FI. Tramposch KM, et al. Among authors: nettleton do. Biochem Biophys Res Commun. 1992 Nov 30;189(1):272-9. doi: 10.1016/0006-291x(92)91554-4. Biochem Biophys Res Commun. 1992. PMID: 1449483

6

Inhibitor of phospholipase A2 blocks eicosanoid and platelet activating factor biosynthesis and has topical anti-inflammatory activity.

Tramposch KM, Chilton FH, Stanley PL, Franson RC, Havens MB, Nettleton DO, Davern LB, Darling IM, Bonney RJ. Tramposch KM, et al. Among authors: nettleton do. J Pharmacol Exp Ther. 1994 Nov;271(2):852-9. J Pharmacol Exp Ther. 1994. PMID: 7965805

7

Swine as a model of skin inflammation. Phospholipase A2-induced inflammation.

Nair X, Nettleton D, Clever D, Tramposch KM, Ghosh S, Franson RC. Nair X, et al. Inflammation. 1993 Apr;17(2):205-15. doi: 10.1007/BF00916106. Inflammation. 1993. PMID: 8491515

8

Preclinical pharmacology of CP-424,391, an orally active pyrazolinone-piperidine [correction of pyrazolidinone-piperidine] growth hormone secretagogue.

Pan LC, Carpino PA, Lefker BA, Ragan JA, Toler SM, Pettersen JC, Nettleton DO, Ng O, Pirie CM, Chidsey-Frink K, Lu B, Nickerson DF, Tess DA, Mullins MA, MacLean DB, DaSilva-Jardine PA, Thompson DD. Pan LC, et al. Among authors: nettleton do. Endocrine. 2001 Feb;14(1):121-32. doi: 10.1385/endo:14:1:121. Endocrine. 2001. PMID: 11322494

9

Multiplexing G protein-coupled receptors in microarrays: a radioligand-binding assay.

Posner B, Hong Y, Benvenuti E, Potchoiba M, Nettleton D, Lui L, Ferrie A, Lai F, Fang Y, Miret J, Wielis C, Webb B. Posner B, et al. Anal Biochem. 2007 Jun 15;365(2):266-73. doi: 10.1016/j.ab.2007.03.014. Epub 2007 Mar 18. Anal Biochem. 2007. PMID: 17459319

10

Simple strategies for reducing sample loads in in vitro metabolic stability high-throughput screening experiments: a comparison between traditional, two-time-point and pooled sample analyses.

Zhao SX, Forman D, Wallace N, Smith BJ, Meyer D, Kazolias D, Gao F, Soglia J, Cole M, Nettleton D. Zhao SX, et al. J Pharm Sci. 2005 Jan;94(1):38-45. doi: 10.1002/jps.20213. J Pharm Sci. 2005. PMID: 15761928

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