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GPC-100, a novel CXCR4 antagonist, improves in vivo hematopoietic cell mobilization when combined with propranolol.
Sukhtankar DD, Fung JJ, Kim MN, Cayton T, Chiou V, Caculitan NG, Zalicki P, Kim S, Jo Y, Kim S, Lee JM, Choi J, Mun S, Chin A, Jang Y, Lee JY, Kim G, Kim EH, Huh WK, Jeong JY, Seen DS, Cardarelli PM. Sukhtankar DD, et al. Among authors: cardarelli pm. PLoS One. 2023 Oct 25;18(10):e0287863. doi: 10.1371/journal.pone.0287863. eCollection 2023. PLoS One. 2023. PMID: 37878624 Free PMC article.
Pharmacokinetics and Pharmacodynamics of Burixafor Hydrobromide (GPC-100), a Novel C-X-C Chemokine Receptor 4 Antagonist and Mobilizer of Hematopoietic Stem/Progenitor Cells, in Mice and Healthy Subjects.
Sukhtankar DD, Chang LW, Tsai CY, Cardarelli PM, Caculitan NG. Sukhtankar DD, et al. Among authors: cardarelli pm. Clin Pharmacol Drug Dev. 2023 Nov;12(11):1114-1120. doi: 10.1002/cpdd.1302. Epub 2023 Aug 4. Clin Pharmacol Drug Dev. 2023. PMID: 37539772 Clinical Trial.
A Cationic Contrast Agent in X-ray Imaging of Articular Cartilage: Pre-Clinical Evaluation of Diffusion and Attenuation Properties.
Fantoni S, Gabucci I, Cardarelli P, Paternò G, Taibi A, Cristofori V, Trapella C, Bazzani A, Assenza M, Zanna Bonacorsi A, Conti D, Baruffaldi F. Fantoni S, et al. Among authors: cardarelli p. Diagnostics (Basel). 2022 Aug 31;12(9):2111. doi: 10.3390/diagnostics12092111. Diagnostics (Basel). 2022. PMID: 36140512 Free PMC article.
DNA-Model-Based Design and Execution of Some Fused Benzodiazepine Hybrid Payloads for Antibody-Drug Conjugate Modality.
Sivaprakasam P, McDonald I, Iwuagwu C, Chowdari NS, Peese KM, Langley DR, Cheng H, Luzung MR, Schmidt MA, Zheng B, Tan Y, Cho P, Rakshit S, Lakshminarasimhan T, Guturi S, Kanagavel K, Kanusu U, Niyogi AG, Sidhar S, Vaidyanathan R, Eastgate MD, Kotapati S, Deshpande M, Pan C, Cardarelli PM, Xie C, Rao C, Holder P, Sarma G, Vite G, Gangwar S. Sivaprakasam P, et al. Among authors: cardarelli pm. ACS Med Chem Lett. 2021 Feb 10;12(3):404-412. doi: 10.1021/acsmedchemlett.0c00578. eCollection 2021 Mar 11. ACS Med Chem Lett. 2021. PMID: 33738068 Free PMC article.
Design, Synthesis, and Structure-Activity Relationships of Novel Tetrahydroisoquinolino Benzodiazepine Dimer Antitumor Agents and Their Application in Antibody-Drug Conjugates.
Chowdari NS, Zhang Y, McDonald I, Johnson W, Langley DR, Sivaprakasam P, Mate R, Huynh T, Kotapati S, Deshpande M, Pan C, Menezes D, Wang Y, Rao C, Sarma G, Warrack BM, Rangan VS, Mei-Chen S, Cardarelli P, Deshpande S, Passmore D, Rampulla R, Mathur A, Borzilleri R, Rajpal A, Vite G, Gangwar S. Chowdari NS, et al. Among authors: cardarelli p. J Med Chem. 2020 Nov 25;63(22):13913-13950. doi: 10.1021/acs.jmedchem.0c01385. Epub 2020 Nov 6. J Med Chem. 2020. PMID: 33155811
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