Lefort K - Search Results

1

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.

Ayyanan A, Civenni G, Ciarloni L, Morel C, Mueller N, Lefort K, Mandinova A, Raffoul W, Fiche M, Dotto GP, Brisken C. Ayyanan A, et al. Among authors: lefort k. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3799-804. doi: 10.1073/pnas.0600065103. Epub 2006 Feb 24. Proc Natl Acad Sci U S A. 2006. PMID: 16501043 Free PMC article.

2

Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression.

Lefort K, Dotto GP. Lefort K, et al. Semin Cancer Biol. 2004 Oct;14(5):374-86. doi: 10.1016/j.semcancer.2004.04.017. Semin Cancer Biol. 2004. PMID: 15288263 Review.

3

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases.

Lefort K, Mandinova A, Ostano P, Kolev V, Calpini V, Kolfschoten I, Devgan V, Lieb J, Raffoul W, Hohl D, Neel V, Garlick J, Chiorino G, Dotto GP. Lefort K, et al. Genes Dev. 2007 Mar 1;21(5):562-77. doi: 10.1101/gad.1484707. Genes Dev. 2007. PMID: 17344417 Free PMC article.

4

Control of hair follicle cell fate by underlying mesenchyme through a CSL-Wnt5a-FoxN1 regulatory axis.

Hu B, Lefort K, Qiu W, Nguyen BC, Rajaram RD, Castillo E, He F, Chen Y, Angel P, Brisken C, Dotto GP. Hu B, et al. Among authors: lefort k. Genes Dev. 2010 Jul 15;24(14):1519-32. doi: 10.1101/gad.1886910. Genes Dev. 2010. PMID: 20634318 Free PMC article.

5

p63 and epithelial metaplasia: a gutsy choice.

Lefort K, Dotto GP. Lefort K, et al. Cell. 2011 Jun 24;145(7):1003-5. doi: 10.1016/j.cell.2011.06.008. Cell. 2011. PMID: 21703442 Free article.

6

IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes.

Restivo G, Nguyen BC, Dziunycz P, Ristorcelli E, Ryan RJ, Özuysal ÖY, Di Piazza M, Radtke F, Dixon MJ, Hofbauer GF, Lefort K, Dotto GP. Restivo G, et al. Among authors: lefort k. EMBO J. 2011 Nov 16;30(22):4571-85. doi: 10.1038/emboj.2011.325. EMBO J. 2011. PMID: 21909072 Free PMC article.

7

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation.

Procopio MG, Laszlo C, Al Labban D, Kim DE, Bordignon P, Jo SH, Goruppi S, Menietti E, Ostano P, Ala U, Provero P, Hoetzenecker W, Neel V, Kilarski WW, Swartz MA, Brisken C, Lefort K, Dotto GP. Procopio MG, et al. Among authors: lefort k. Nat Cell Biol. 2015 Sep;17(9):1193-204. doi: 10.1038/ncb3228. Epub 2015 Aug 24. Nat Cell Biol. 2015. PMID: 26302407 Free PMC article.

8

Negative control of CSL gene transcription by stress/DNA damage response and p53.

Menietti E, Xu X, Ostano P, Joseph JM, Lefort K, Dotto GP. Menietti E, et al. Among authors: lefort k. Cell Cycle. 2016 Jul 2;15(13):1767-78. doi: 10.1080/15384101.2016.1186317. Epub 2016 May 10. Cell Cycle. 2016. PMID: 27163456 Free PMC article.

9

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation.

Nguyen BC, Lefort K, Mandinova A, Antonini D, Devgan V, Della Gatta G, Koster MI, Zhang Z, Wang J, Tommasi di Vignano A, Kitajewski J, Chiorino G, Roop DR, Missero C, Dotto GP. Nguyen BC, et al. Among authors: lefort k. Genes Dev. 2006 Apr 15;20(8):1028-42. doi: 10.1101/gad.1406006. Genes Dev. 2006. PMID: 16618808 Free PMC article.

10

The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response.

Mandinova A, Lefort K, Tommasi di Vignano A, Stonely W, Ostano P, Chiorino G, Iwaki H, Nakanishi J, Dotto GP. Mandinova A, et al. Among authors: lefort k. EMBO J. 2008 Apr 23;27(8):1243-54. doi: 10.1038/emboj.2008.45. Epub 2008 Apr 3. EMBO J. 2008. PMID: 18388864 Free PMC article.

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