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Latent genetic backgrounds and molecular pathogenesis in drug-induced long-QT syndrome.
Itoh H, Sakaguchi T, Ding WG, Watanabe E, Watanabe I, Nishio Y, Makiyama T, Ohno S, Akao M, Higashi Y, Zenda N, Kubota T, Mori C, Okajima K, Haruna T, Miyamoto A, Kawamura M, Ishida K, Nagaoka I, Oka Y, Nakazawa Y, Yao T, Jo H, Sugimoto Y, Ashihara T, Hayashi H, Ito M, Imoto K, Matsuura H, Horie M. Itoh H, et al. Among authors: ito m. Circ Arrhythm Electrophysiol. 2009 Oct;2(5):511-23. doi: 10.1161/CIRCEP.109.862649. Epub 2009 Aug 2. Circ Arrhythm Electrophysiol. 2009. PMID: 19843919
A novel KCNH2 mutation as a modifier for short QT interval.
Itoh H, Sakaguchi T, Ashihara T, Ding WG, Nagaoka I, Oka Y, Nakazawa Y, Yao T, Jo H, Ito M, Nakamura K, Ohe T, Matsuura H, Horie M. Itoh H, et al. Among authors: ito m. Int J Cardiol. 2009 Sep 11;137(1):83-5. doi: 10.1016/j.ijcard.2008.05.050. Epub 2008 Aug 9. Int J Cardiol. 2009. PMID: 18692916
Hydroxyzine, a first generation H(1)-receptor antagonist, inhibits human ether-a-go-go-related gene (HERG) current and causes syncope in a patient with the HERG mutation.
Sakaguchi T, Itoh H, Ding WG, Tsuji K, Nagaoka I, Oka Y, Ashihara T, Ito M, Yumoto Y, Zenda N, Higashi Y, Takeyama Y, Matsuura H, Horie M. Sakaguchi T, et al. Among authors: ito m. J Pharmacol Sci. 2008 Dec;108(4):462-71. doi: 10.1254/jphs.08178fp. Epub 2008 Dec 5. J Pharmacol Sci. 2008. PMID: 19057127 Free article.
Risk determinants in individuals with a spontaneous type 1 Brugada ECG.
Miyamoto A, Hayashi H, Makiyama T, Yoshino T, Mizusawa Y, Sugimoto Y, Ito M, Xue JQ, Murakami Y, Horie M. Miyamoto A, et al. Among authors: ito m. Circ J. 2011;75(4):844-51. doi: 10.1253/circj.cj-10-0903. Epub 2011 Feb 18. Circ J. 2011. PMID: 21343656 Free article.
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