Elongation factor Ts can act as a steric chaperone by increasing the solubility of nucleotide binding-impaired elongation factor-Tu.
Krab IM, te Biesebeke R, Bernardi A, Parmeggiani A.
Krab IM, et al. Among authors: parmeggiani a.
Biochemistry. 2001 Jul 24;40(29):8531-5. doi: 10.1021/bi0104930.
Biochemistry. 2001.
PMID: 11456491
Moreover, EF-Tu[T25A] and EF-Tu[D80N] were shown to inhibit cell growth on expression, an effect attributed to their sequestration of EF-Ts [Krab, I. M., and Parmeggiani, A. (1999) J. Biol. Chem. 274, 11132--11138; Krab, I. M., and Parmeggiani, A. (199 …
Moreover, EF-Tu[T25A] and EF-Tu[D80N] were shown to inhibit cell growth on expression, an effect attributed to their sequestration of EF-Ts …