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An alpha-mercaptoacrylic acid derivative (PD150606) inhibits selective motor neuron death via inhibition of kainate-induced Ca2+ influx and not via calpain inhibition.
Van den Bosch L, Van Damme P, Vleminckx V, Van Houtte E, Lemmens G, Missiaen L, Callewaert G, Robberecht W. Van den Bosch L, et al. Among authors: van damme p, van houtte e. Neuropharmacology. 2002 Apr;42(5):706-13. doi: 10.1016/s0028-3908(02)00010-2. Neuropharmacology. 2002. PMID: 11985829
Excitotoxicity and amyotrophic lateral sclerosis.
Van Damme P, Dewil M, Robberecht W, Van Den Bosch L. Van Damme P, et al. Among authors: van den bosch l. Neurodegener Dis. 2005;2(3-4):147-59. doi: 10.1159/000089620. Neurodegener Dis. 2005. PMID: 16909020 Review.
Progranulin genetic variability contributes to amyotrophic lateral sclerosis.
Sleegers K, Brouwers N, Maurer-Stroh S, van Es MA, Van Damme P, van Vught PW, van der Zee J, Serneels S, De Pooter T, Van den Broeck M, Cruts M, Schymkowitz J, De Jonghe P, Rousseau F, van den Berg LH, Robberecht W, Van Broeckhoven C. Sleegers K, et al. Among authors: van es ma, van den broeck m, van damme p, van den berg lh, van der zee j, van vught pw, van broeckhoven c. Neurology. 2008 Jul 22;71(4):253-9. doi: 10.1212/01.wnl.0000289191.54852.75. Epub 2008 Jan 9. Neurology. 2008. PMID: 18184915
TDP-43 M311V mutation in familial amyotrophic lateral sclerosis.
Lemmens R, Race V, Hersmus N, Matthijs G, Van Den Bosch L, Van Damme P, Dubois B, Boonen S, Goris A, Robberecht W. Lemmens R, et al. Among authors: van damme p, van den bosch l. J Neurol Neurosurg Psychiatry. 2009 Mar;80(3):354-5. doi: 10.1136/jnnp.2008.157677. J Neurol Neurosurg Psychiatry. 2009. PMID: 19228676 No abstract available.
Tau levels do not influence human ALS or motor neuron degeneration in the SOD1G93A mouse.
Taes I, Goris A, Lemmens R, van Es MA, van den Berg LH, Chio A, Traynor BJ, Birve A, Andersen P, Slowik A, Tomik B, Brown RH Jr, Shaw CE, Al-Chalabi A, Boonen S, Van Den Bosch L, Dubois B, Van Damme P, Robberecht W. Taes I, et al. Among authors: van es ma, van den berg lh, van damme p, van den bosch l. Neurology. 2010 May 25;74(21):1687-93. doi: 10.1212/WNL.0b013e3181e042f7. Neurology. 2010. PMID: 20498436 Free PMC article.
1,227 results