Fox CB - Search Results

1

Separation of alpha 1 adrenergic and N-methyl-D-aspartate antagonist activity in a series of ifenprodil compounds.

Chenard BL, Shalaby IA, Koe BK, Ronau RT, Butler TW, Prochniak MA, Schmidt AW, Fox CB. Chenard BL, et al. Among authors: fox cb. J Med Chem. 1991 Oct;34(10):3085-90. doi: 10.1021/jm00114a018. J Med Chem. 1991. PMID: 1681106

2

1-(2-Aminoethyl)-3-methyl-8,9-dihydropyrano[3,2-e]indole: a rotationally restricted phenolic analog of the neurotransmitter serotonin and agonist selective for serotonin (5-HT2-type) receptors.

Macor JE, Fox CB, Johnson C, Koe BK, Lebel LA, Zorn SH. Macor JE, et al. Among authors: fox cb. J Med Chem. 1992 Oct 2;35(20):3625-32. doi: 10.1021/jm00098a005. J Med Chem. 1992. PMID: 1433172

3

Synthesis and serotonergic pharmacology of the enantiomers of 3-[(N-methylpyrrolidin-2-yl)methyl]-5-methoxy-1H-indole: discovery of stereogenic differentiation in the aminoethyl side chain of the neurotransmitter serotonin.

Macor JE, Blake J, Fox CB, Johnson C, Koe BK, Lebel LA, Morrone JM, Ryan K, Schmidt AW, Schulz DW, et al. Macor JE, et al. Among authors: fox cb. J Med Chem. 1992 Nov 13;35(23):4503-5. doi: 10.1021/jm00101a032. J Med Chem. 1992. PMID: 1447752 No abstract available.

4

(1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: a potent new neuroprotectant which blocks N-methyl-D-aspartate responses.

Chenard BL, Bordner J, Butler TW, Chambers LK, Collins MA, De Costa DL, Ducat MF, Dumont ML, Fox CB, Mena EE, et al. Chenard BL, et al. Among authors: fox cb. J Med Chem. 1995 Aug 4;38(16):3138-45. doi: 10.1021/jm00016a017. J Med Chem. 1995. PMID: 7636876

5

5-[(3-nitropyrid-2-yl)amino]indoles: novel serotonin agonists with selectivity for the 5-HT1D receptor. Variation of the C3 substituent on the indole template leads to increased 5-HT1D receptor selectivity.

Macor JE, Blank DH, Fox CB, Lebel LA, Newman ME, Post RJ, Ryan K, Schmidt AW, Schulz DW, Koe BK. Macor JE, et al. Among authors: fox cb. J Med Chem. 1994 Aug 5;37(16):2509-12. doi: 10.1021/jm00042a003. J Med Chem. 1994. PMID: 8057297 No abstract available.

6

Characterization of [3H]CP-96,501 as a selective radioligand for the serotonin 5-HT1B receptor: binding studies in rat brain membranes.

Koe BK, Lebel LA, Fox CB, Macor JE. Koe BK, et al. Among authors: fox cb. J Neurochem. 1992 Apr;58(4):1268-76. doi: 10.1111/j.1471-4159.1992.tb11338.x. J Neurochem. 1992. PMID: 1548463

7

3,5-Bicyclic aryl piperidines: a novel class of alpha4beta2 neuronal nicotinic receptor partial agonists for smoking cessation.

Coe JW, Brooks PR, Wirtz MC, Bashore CG, Bianco KE, Vetelino MG, Arnold EP, Lebel LA, Fox CB, Tingley FD 3rd, Schulz DW, Davis TI, Sands SB, Mansbach RS, Rollema H, O'Neill BT. Coe JW, et al. Among authors: fox cb. Bioorg Med Chem Lett. 2005 Nov 15;15(22):4889-97. doi: 10.1016/j.bmcl.2005.08.035. Bioorg Med Chem Lett. 2005. PMID: 16171993

8

Use of structure-based design to discover a potent, selective, in vivo active phosphodiesterase 10A inhibitor lead series for the treatment of schizophrenia.

Helal CJ, Kang Z, Hou X, Pandit J, Chappie TA, Humphrey JM, Marr ES, Fennell KF, Chenard LK, Fox C, Schmidt CJ, Williams RD, Chapin DS, Siuciak J, Lebel L, Menniti F, Cianfrogna J, Fonseca KR, Nelson FR, O'Connor R, MacDougall M, McDowell L, Liras S. Helal CJ, et al. J Med Chem. 2011 Jul 14;54(13):4536-47. doi: 10.1021/jm2001508. Epub 2011 Jun 8. J Med Chem. 2011. PMID: 21650160

9

Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.

Chappie TA, Humphrey JM, Allen MP, Estep KG, Fox CB, Lebel LA, Liras S, Marr ES, Menniti FS, Pandit J, Schmidt CJ, Tu M, Williams RD, Yang FV. Chappie TA, et al. Among authors: fox cb. J Med Chem. 2007 Jan 25;50(2):182-5. doi: 10.1021/jm060653b. J Med Chem. 2007. PMID: 17228859

10

In pursuit of alpha4beta2 nicotinic receptor partial agonists for smoking cessation: carbon analogs of (-)-cytisine.

Coe JW, Vetelino MG, Bashore CG, Wirtz MC, Brooks PR, Arnold EP, Lebel LA, Fox CB, Sands SB, Davis TI, Schulz DW, Rollema H, Tingley FD 3rd, O'Neill BT. Coe JW, et al. Among authors: fox cb. Bioorg Med Chem Lett. 2005 Jun 15;15(12):2974-9. doi: 10.1016/j.bmcl.2005.04.036. Bioorg Med Chem Lett. 2005. PMID: 15908213

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