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Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors.
Li H, Tatlock J, Linton A, Gonzalez J, Borchardt A, Dragovich P, Jewell T, Prins T, Zhou R, Blazel J, Parge H, Love R, Hickey M, Doan C, Shi S, Duggal R, Lewis C, Fuhrman S. Li H, et al. Among authors: duggal r. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4834-8. doi: 10.1016/j.bmcl.2006.06.065. Epub 2006 Jul 7. Bioorg Med Chem Lett. 2006. PMID: 16824756
In vitro resistance study of AG-021541, a novel nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Shi ST, Herlihy KJ, Graham JP, Fuhrman SA, Doan C, Parge H, Hickey M, Gao J, Yu X, Chau F, Gonzalez J, Li H, Lewis C, Patick AK, Duggal R. Shi ST, et al. Among authors: duggal r. Antimicrob Agents Chemother. 2008 Feb;52(2):675-83. doi: 10.1128/AAC.00834-07. Epub 2007 Dec 10. Antimicrob Agents Chemother. 2008. PMID: 18070954 Free PMC article.
PSMA-targeted bispecific Fab conjugates that engage T cells.
Patterson JT, Isaacson J, Kerwin L, Atassi G, Duggal R, Bresson D, Zhu T, Zhou H, Fu Y, Kaufmann GF. Patterson JT, et al. Among authors: duggal r. Bioorg Med Chem Lett. 2017 Dec 15;27(24):5490-5495. doi: 10.1016/j.bmcl.2017.09.065. Epub 2017 Oct 6. Bioorg Med Chem Lett. 2017. PMID: 29126850
207 results