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Cell surface glypicans are low-affinity endostatin receptors.
Karumanchi SA, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, Dhanabal M, Hanai JI, Venkataraman G, Shriver Z, Keiser N, Kalluri R, Zeng H, Mukhopadhyay D, Chen RL, Lander AD, Hagihara K, Yamaguchi Y, Sasisekharan R, Cantley L, Sukhatme VP. Karumanchi SA, et al. Mol Cell. 2001 Apr;7(4):811-22. doi: 10.1016/s1097-2765(01)00225-8. Mol Cell. 2001. PMID: 11336704 Free article.
Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud.
Karihaloo A, Karumanchi SA, Barasch J, Jha V, Nickel CH, Yang J, Grisaru S, Bush KT, Nigam S, Rosenblum ND, Sukhatme VP, Cantley LG. Karihaloo A, et al. Among authors: karumanchi sa. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12509-14. doi: 10.1073/pnas.221205198. Epub 2001 Oct 16. Proc Natl Acad Sci U S A. 2001. PMID: 11606725 Free PMC article.
Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1.
Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP. Hanai J, et al. Among authors: karumanchi sa. J Biol Chem. 2002 May 10;277(19):16464-9. doi: 10.1074/jbc.M112274200. Epub 2002 Jan 28. J Biol Chem. 2002. PMID: 11815623 Free article.
Endostatin is a potential inhibitor of Wnt signaling.
Hanai J, Gloy J, Karumanchi SA, Kale S, Tang J, Hu G, Chan B, Ramchandran R, Jha V, Sukhatme VP, Sokol S. Hanai J, et al. Among authors: karumanchi sa. J Cell Biol. 2002 Aug 5;158(3):529-39. doi: 10.1083/jcb.200203064. Epub 2002 Jul 29. J Cell Biol. 2002. PMID: 12147676 Free PMC article.
Cellular actions and signaling by endostatin.
Ramchandran R, Karumanchi SA, Hanai J, Alper SL, Sukhatme VP. Ramchandran R, et al. Among authors: karumanchi sa. Crit Rev Eukaryot Gene Expr. 2002;12(3):175-91. doi: 10.1615/critreveukaryotgeneexpr.v12.i3.20. Crit Rev Eukaryot Gene Expr. 2002. PMID: 12449342 Free PMC article. Review.
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, Libermann TA, Morgan JP, Sellke FW, Stillman IE, Epstein FH, Sukhatme VP, Karumanchi SA. Maynard SE, et al. Among authors: karumanchi sa. J Clin Invest. 2003 Mar;111(5):649-58. doi: 10.1172/JCI17189. J Clin Invest. 2003. PMID: 12618519 Free PMC article.
356 results