Gall I - Search Results

1

Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells.

Stefan E, Wiesner B, Baillie GS, Mollajew R, Henn V, Lorenz D, Furkert J, Santamaria K, Nedvetsky P, Hundsrucker C, Beyermann M, Krause E, Pohl P, Gall I, MacIntyre AN, Bachmann S, Houslay MD, Rosenthal W, Klussmann E. Stefan E, et al. Among authors: gall i. J Am Soc Nephrol. 2007 Jan;18(1):199-212. doi: 10.1681/ASN.2006020132. Epub 2006 Nov 29. J Am Soc Nephrol. 2007. PMID: 17135396

2

beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi.

Baillie GS, Sood A, McPhee I, Gall I, Perry SJ, Lefkowitz RJ, Houslay MD. Baillie GS, et al. Among authors: gall i. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):940-5. doi: 10.1073/pnas.262787199. Epub 2003 Jan 27. Proc Natl Acad Sci U S A. 2003. PMID: 12552097 Free PMC article. Retracted.

3

Oxidative stress employs phosphatidyl inositol 3-kinase and ERK signalling pathways to activate cAMP phosphodiesterase-4D3 (PDE4D3) through multi-site phosphorylation at Ser239 and Ser579.

Hill EV, Sheppard CL, Cheung YF, Gall I, Krause E, Houslay MD. Hill EV, et al. Among authors: gall i. Cell Signal. 2006 Nov;18(11):2056-69. doi: 10.1016/j.cellsig.2006.07.018. Epub 2006 Aug 1. Cell Signal. 2006. PMID: 16973330

4

Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2+.

Huston E, Gall I, Houslay TM, Houslay MD. Huston E, et al. Among authors: gall i. J Cell Sci. 2006 Sep 15;119(Pt 18):3799-810. doi: 10.1242/jcs.03106. Epub 2006 Aug 29. J Cell Sci. 2006. PMID: 16940352

5

Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process.

Terry R, Cheung YF, Praestegaard M, Baillie GS, Huston E, Gall I, Adams DR, Houslay MD. Terry R, et al. Among authors: gall i. Cell Signal. 2003 Oct;15(10):955-71. doi: 10.1016/s0898-6568(03)00092-5. Cell Signal. 2003. PMID: 12873709

6

PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6).

Cheung YF, Kan Z, Garrett-Engele P, Gall I, Murdoch H, Baillie GS, Camargo LM, Johnson JM, Houslay MD, Castle JC. Cheung YF, et al. Among authors: gall i. J Pharmacol Exp Ther. 2007 Aug;322(2):600-9. doi: 10.1124/jpet.107.122218. Epub 2007 May 22. J Pharmacol Exp Ther. 2007. PMID: 17519386 Free article.

7

In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.

McCahill A, McSorley T, Huston E, Hill EV, Lynch MJ, Gall I, Keryer G, Lygren B, Tasken K, van Heeke G, Houslay MD. McCahill A, et al. Among authors: gall i. Cell Signal. 2005 Sep;17(9):1158-73. doi: 10.1016/j.cellsig.2005.04.003. Cell Signal. 2005. PMID: 15905070

8

Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene.

Wallace DA, Johnston LA, Huston E, MacMaster D, Houslay TM, Cheung YF, Campbell L, Millen JE, Smith RA, Gall I, Knowles RG, Sullivan M, Houslay MD. Wallace DA, et al. Among authors: gall i. Mol Pharmacol. 2005 Jun;67(6):1920-34. doi: 10.1124/mol.104.009423. Epub 2005 Feb 28. Mol Pharmacol. 2005. PMID: 15738310

9

TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid.

Baillie GS, Huston E, Scotland G, Hodgkin M, Gall I, Peden AH, MacKenzie C, Houslay ES, Currie R, Pettitt TR, Walmsley AR, Wakelam MJ, Warwicker J, Houslay MD. Baillie GS, et al. Among authors: gall i. J Biol Chem. 2002 Aug 2;277(31):28298-309. doi: 10.1074/jbc.M108353200. Epub 2002 May 6. J Biol Chem. 2002. PMID: 11994273 Free article.

10

In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting.

Beard MB, Huston E, Campbell L, Gall I, McPhee I, Yarwood S, Scotland G, Houslay MD. Beard MB, et al. Among authors: gall i. Cell Signal. 2002 May;14(5):453-65. doi: 10.1016/s0898-6568(01)00264-9. Cell Signal. 2002. PMID: 11882390

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