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The benzylthio-pyrimidine U-31,355, a potent inhibitor of HIV-1 reverse transcriptase.
Althaus IW, Chou KC, Lemay RJ, Franks KM, Deibel MR, Kezdy FJ, Resnick L, Busso ME, So AG, Downey KM, Romero DL, Thomas RC, Aristoff PA, Tarpley WG, Reusser F. Althaus IW, et al. Among authors: aristoff pa. Biochem Pharmacol. 1996 Mar 22;51(6):743-50. doi: 10.1016/0006-2952(95)02390-9. Biochem Pharmacol. 1996. PMID: 8602869 Free article.
Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitors.
Thaisrivongs S, Romero DL, Tommasi RA, Janakiraman MN, Strohbach JW, Turner SR, Biles C, Morge RR, Johnson PD, Aristoff PA, Tomich PK, Lynn JC, Horng MM, Chong KT, Hinshaw RR, Howe WJ, Finzel BC, Watenpaugh KD. Thaisrivongs S, et al. Among authors: aristoff pa. J Med Chem. 1996 Nov 8;39(23):4630-42. doi: 10.1021/jm960228q. J Med Chem. 1996. PMID: 8917652
Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitors.
Thaisrivongs S, Skulnick HI, Turner SR, Strohbach JW, Tommasi RA, Johnson PD, Aristoff PA, Judge TM, Gammill RB, Morris JK, Romines KR, Chrusciel RA, Hinshaw RR, Chong KT, Tarpley WG, Poppe SM, Slade DE, Lynn JC, Horng MM, Tomich PK, Seest EP, Dolak LA, Howe WJ, Howard GM, Watenpaugh KD, et al. Thaisrivongs S, et al. Among authors: aristoff pa. J Med Chem. 1996 Oct 25;39(22):4349-53. doi: 10.1021/jm960541s. J Med Chem. 1996. PMID: 8893827 No abstract available.
35 results