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Synthesis and SAR of thiophene containing kinesin spindle protein (KSP) inhibitors.
Pinkerton AB, Lee TT, Hoffman TZ, Wang Y, Kahraman M, Cook TG, Severance D, Gahman TC, Noble SA, Shiau AK, Davis RL. Pinkerton AB, et al. Among authors: severance d. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3562-9. doi: 10.1016/j.bmcl.2007.04.076. Epub 2007 Apr 29. Bioorg Med Chem Lett. 2007. PMID: 17498954
Discovery of inducible nitric oxide synthase (iNOS) inhibitor development candidate KD7332, part 1: Identification of a novel, potent, and selective series of quinolinone iNOS dimerization inhibitors that are orally active in rodent pain models.
Bonnefous C, Payne JE, Roppe J, Zhuang H, Chen X, Symons KT, Nguyen PM, Sablad M, Rozenkrants N, Zhang Y, Wang L, Severance D, Walsh JP, Yazdani N, Shiau AK, Noble SA, Rix P, Rao TS, Hassig CA, Smith ND. Bonnefous C, et al. Among authors: severance d. J Med Chem. 2009 May 14;52(9):3047-62. doi: 10.1021/jm900173b. J Med Chem. 2009. PMID: 19374401
Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR.
Ansari A, Satalkar S, Patil V, Shete AS, Kaur S, Gupta A, Singh S, Raja M, Severance DL, Bernales S, Chakravarty S, Hung DT, Pham SM, Herrera FJ, Rai R. Ansari A, et al. Among authors: severance dl. Bioorg Med Chem Lett. 2017 Jan 15;27(2):217-222. doi: 10.1016/j.bmcl.2016.11.080. Epub 2016 Nov 25. Bioorg Med Chem Lett. 2017. PMID: 27923618
Molecular characterization of the gerbil C5a receptor and identification of a transmembrane domain V amino acid that is crucial for small molecule antagonist interaction.
Waters SM, Brodbeck RM, Steflik J, Yu J, Baltazar C, Peck AE, Severance D, Zhang LY, Currie K, Chenard BL, Hutchison AJ, Maynard G, Krause JE. Waters SM, et al. Among authors: severance d. J Biol Chem. 2005 Dec 9;280(49):40617-23. doi: 10.1074/jbc.M509245200. Epub 2005 Oct 17. J Biol Chem. 2005. PMID: 16230349 Free article.
Pattern for genocide.
Severance G, Severance D. Severance G, et al. Among authors: severance d. New Engl J Hist. 2002-2003;59(2-3):42-69. New Engl J Hist. 2002. PMID: 20191685 No abstract available.
The Frontier Nursing Service.
Severance D. Severance D. Front Nurs Serv Q Bull. 1996 Fall;72(2):1-2. Front Nurs Serv Q Bull. 1996. PMID: 9281933 No abstract available.
FNS plans for birthing center.
Severance D. Severance D. Front Nurs Serv Q Bull. 1993 Summer;69(1):7-8. Front Nurs Serv Q Bull. 1993. PMID: 8406289 No abstract available.
17 results