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Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth.
Mellick AS, Plummer PN, Nolan DJ, Gao D, Bambino K, Hahn M, Catena R, Turner V, McDonnell K, Benezra R, Brink R, Swarbrick A, Mittal V. Mellick AS, et al. Among authors: nolan dj. Cancer Res. 2010 Sep 15;70(18):7273-82. doi: 10.1158/0008-5472.CAN-10-1142. Epub 2010 Aug 31. Cancer Res. 2010. PMID: 20807818 Free PMC article.
Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas.
Kerbel RS, Benezra R, Lyden DC, Hattori K, Heissig B, Nolan DJ, Mittal V, Shaked Y, Dias S, Bertolini F, Rafii S. Kerbel RS, et al. Among authors: nolan dj. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):E54; author reply E55. doi: 10.1073/pnas.0804876105. Epub 2008 Aug 20. Proc Natl Acad Sci U S A. 2008. PMID: 18715995 Free PMC article. No abstract available.
162 results