MacCarthy T - Search Results

1

Coevolution of robustness, epistasis, and recombination favors asexual reproduction.

MacCarthy T, Bergman A. MacCarthy T, et al. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12801-6. doi: 10.1073/pnas.0705455104. Epub 2007 Jul 23. Proc Natl Acad Sci U S A. 2007. PMID: 17646644 Free PMC article.

2

Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.

Roa S, Avdievich E, Peled JU, Maccarthy T, Werling U, Kuang FL, Kan R, Zhao C, Bergman A, Cohen PE, Edelmann W, Scharff MD. Roa S, et al. Among authors: maccarthy t. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16248-53. doi: 10.1073/pnas.0808182105. Epub 2008 Oct 14. Proc Natl Acad Sci U S A. 2008. PMID: 18854411 Free PMC article.

3

V-region mutation in vitro, in vivo, and in silico reveal the importance of the enzymatic properties of AID and the sequence environment.

MacCarthy T, Kalis SL, Roa S, Pham P, Goodman MF, Scharff MD, Bergman A. MacCarthy T, et al. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8629-34. doi: 10.1073/pnas.0903803106. Epub 2009 May 14. Proc Natl Acad Sci U S A. 2009. PMID: 19443686 Free PMC article.

4

A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation.

Wontakal SN, Guo X, Smith C, MacCarthy T, Bresnick EH, Bergman A, Snyder MP, Weissman SM, Zheng D, Skoultchi AI. Wontakal SN, et al. Among authors: maccarthy t. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3832-7. doi: 10.1073/pnas.1121019109. Epub 2012 Feb 22. Proc Natl Acad Sci U S A. 2012. PMID: 22357756 Free PMC article.

5

Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging.

Bergman A, Atzmon G, Ye K, MacCarthy T, Barzilai N. Bergman A, et al. Among authors: maccarthy t. PLoS Comput Biol. 2007 Aug;3(8):e170. doi: 10.1371/journal.pcbi.0030170. Epub 2007 Jul 18. PLoS Comput Biol. 2007. PMID: 17784782 Free PMC article.

6

The limits of subfunctionalization.

MacCarthy T, Bergman A. MacCarthy T, et al. BMC Evol Biol. 2007 Nov 7;7:213. doi: 10.1186/1471-2148-7-213. BMC Evol Biol. 2007. PMID: 17988397 Free PMC article.

7

SHMTool: a webserver for comparative analysis of somatic hypermutation datasets.

Maccarthy T, Roa S, Scharff MD, Bergman A. Maccarthy T, et al. DNA Repair (Amst). 2009 Jan 1;8(1):137-41. doi: 10.1016/j.dnarep.2008.09.006. Epub 2008 Nov 8. DNA Repair (Amst). 2009. PMID: 18952008 Free PMC article.

8

Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in Ramos cells.

Baughn LB, Kalis SL, MacCarthy T, Wei L, Fan M, Bergman A, Scharff MD. Baughn LB, et al. Among authors: maccarthy t. mBio. 2011 Oct 11;2(5):e00186-11. doi: 10.1128/mBio.00186-11. Print 2011. mBio. 2011. PMID: 21990614 Free PMC article.

9

The underlying molecular and network level mechanisms in the evolution of robustness in gene regulatory networks.

Pujato M, MacCarthy T, Fiser A, Bergman A. Pujato M, et al. Among authors: maccarthy t. PLoS Comput Biol. 2013;9(1):e1002865. doi: 10.1371/journal.pcbi.1002865. Epub 2013 Jan 3. PLoS Comput Biol. 2013. PMID: 23300434 Free PMC article.

10

Epigenetics decouples mutational from environmental robustness. Did it also facilitate multicellularity?

Gombar S, MacCarthy T, Bergman A. Gombar S, et al. Among authors: maccarthy t. PLoS Comput Biol. 2014 Mar 6;10(3):e1003450. doi: 10.1371/journal.pcbi.1003450. eCollection 2014 Mar. PLoS Comput Biol. 2014. PMID: 24604070 Free PMC article.

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