Sayers J - Search Results

1

Investigating the interaction between osteoprotegerin and receptor activator of NF-kappaB or tumor necrosis factor-related apoptosis-inducing ligand: evidence for a pivotal role for osteoprotegerin in regulating two distinct pathways.

Vitovski S, Phillips JS, Sayers J, Croucher PI. Vitovski S, et al. Among authors: sayers j. J Biol Chem. 2007 Oct 26;282(43):31601-9. doi: 10.1074/jbc.M706078200. Epub 2007 Aug 15. J Biol Chem. 2007. PMID: 17702740 Free article.

2

Relaxed cleavage specificity of an immunoglobulin A1 protease from Neisseria meningitidis.

Vitovski S, Sayers JR. Vitovski S, et al. Infect Immun. 2007 Jun;75(6):2875-85. doi: 10.1128/IAI.01671-06. Epub 2007 Mar 12. Infect Immun. 2007. PMID: 17353288 Free PMC article.

3

Immunoglobulin A1 proteases: a structure-function update.

Parsons HK, Vitovski S, Sayers JR. Parsons HK, et al. Among authors: sayers jr. Biochem Soc Trans. 2004 Dec;32(Pt 6):1130-2. doi: 10.1042/BST0321130. Biochem Soc Trans. 2004. PMID: 15506988

4

Nontypeable Haemophilus influenzae in carriage and disease: a difference in IgA1 protease activity levels.

Vitovski S, Dunkin KT, Howard AJ, Sayers JR. Vitovski S, et al. Among authors: sayers jr. JAMA. 2002 Apr 3;287(13):1699-705. doi: 10.1001/jama.287.13.1699. JAMA. 2002. PMID: 11926894

5

Continuous affinity-based selection: rapid screening and simultaneous amplification of bacterial surface-display libraries.

Patel D, Vitovski S, Senior HJ, Edge MD, Hockney RC, Dempsey MJ, Sayers JR. Patel D, et al. Among authors: sayers jr. Biochem J. 2001 Aug 1;357(Pt 3):779-85. doi: 10.1042/0264-6021:3570779. Biochem J. 2001. PMID: 11463348 Free PMC article.

6

Invasive isolates of Neisseria meningitidis possess enhanced immunoglobulin A1 protease activity compared to colonizing strains.

Vitovski S, Read RC, Sayers JR. Vitovski S, et al. Among authors: sayers jr. FASEB J. 1999 Feb;13(2):331-7. doi: 10.1096/fasebj.13.2.331. FASEB J. 1999. PMID: 9973321

7

Neutralizing mutations of carboxylates that bind metal 2 in T5 flap endonuclease result in an enzyme that still requires two metal ions.

Tomlinson CG, Syson K, Sengerová B, Atack JM, Sayers JR, Swanson L, Tainer JA, Williams NH, Grasby JA. Tomlinson CG, et al. J Biol Chem. 2011 Sep 2;286(35):30878-30887. doi: 10.1074/jbc.M111.230391. Epub 2011 Jul 6. J Biol Chem. 2011. PMID: 21734257 Free PMC article.

8

Variation in the steady state kinetic parameters of wild type and mutant T5 5'-3'-exonuclease with pH. Protonation of Lys-83 is critical for DNA binding.

Pickering TJ, Garforth S, Sayers JR, Grasby JA. Pickering TJ, et al. Among authors: sayers jr. J Biol Chem. 1999 Jun 18;274(25):17711-7. doi: 10.1074/jbc.274.25.17711. J Biol Chem. 1999. PMID: 10364212 Free article.

9

Three metal ions participate in the reaction catalyzed by T5 flap endonuclease.

Syson K, Tomlinson C, Chapados BR, Sayers JR, Tainer JA, Williams NH, Grasby JA. Syson K, et al. J Biol Chem. 2008 Oct 17;283(42):28741-6. doi: 10.1074/jbc.M801264200. Epub 2008 Aug 11. J Biol Chem. 2008. PMID: 18697748 Free PMC article.

10

Molecular interactions of Escherichia coli ExoIX and identification of its associated 3'-5' exonuclease activity.

Hodskinson MR, Allen LM, Thomson DP, Sayers JR. Hodskinson MR, et al. Nucleic Acids Res. 2007;35(12):4094-102. doi: 10.1093/nar/gkm396. Epub 2007 Jun 12. Nucleic Acids Res. 2007. PMID: 17567612 Free PMC article.

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