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From laboratory to Phase I/II cancer trials with recombinant biotherapeutics.
Tolner B, Smith L, Hillyer T, Bhatia J, Beckett P, Robson L, Sharma SK, Griffin N, Vervecken W, Contreras R, Pedley RB, Begent RH, Chester KA. Tolner B, et al. Among authors: sharma sk. Eur J Cancer. 2007 Nov;43(17):2515-22. doi: 10.1016/j.ejca.2007.08.027. Epub 2007 Oct 22. Eur J Cancer. 2007. PMID: 17933516 Review.
Antibody-directed enzyme prodrug therapy (ADEPT) for cancer.
Bagshawe KD, Sharma SK, Begent RH. Bagshawe KD, et al. Among authors: sharma sk. Expert Opin Biol Ther. 2004 Nov;4(11):1777-89. doi: 10.1517/14712598.4.11.1777. Expert Opin Biol Ther. 2004. PMID: 15500406 Review.
Antibody-enzyme fusion proteins for cancer therapy.
Andrady C, Sharma SK, Chester KA. Andrady C, et al. Among authors: sharma sk. Immunotherapy. 2011 Feb;3(2):193-211. doi: 10.2217/imt.10.90. Immunotherapy. 2011. PMID: 21322759 Review.
Recombinant anti-carcinoembryonic antigen antibodies for targeting cancer.
Chester KA, Mayer A, Bhatia J, Robson L, Spencer DI, Cooke SP, Flynn AA, Sharma SK, Boxer G, Pedley RB, Begent RH. Chester KA, et al. Among authors: sharma sk. Cancer Chemother Pharmacol. 2000;46 Suppl:S8-12. doi: 10.1007/pl00014055. Cancer Chemother Pharmacol. 2000. PMID: 10950140 Review.
Clinical applications of phage-derived sFvs and sFv fusion proteins.
Chester KA, Bhatia J, Boxer G, Cooke SP, Flynn AA, Huhalov A, Mayer A, Pedley RB, Robson L, Sharma SK, Spencer DI, Begent RH. Chester KA, et al. Among authors: sharma sk. Dis Markers. 2000;16(1-2):53-62. doi: 10.1155/2000/672706. Dis Markers. 2000. PMID: 11360829 Free PMC article. Review.
Radiolabelling of glycosylated MFE-23::CPG2 fusion protein (MFECP1) with 99mTc for quantitation of tumour antibody-enzyme localisation in antibody-directed enzyme pro-drug therapy (ADEPT).
Francis RJ, Mather SJ, Chester K, Sharma SK, Bhatia J, Pedley RB, Waibel R, Green AJ, Begent RH. Francis RJ, et al. Among authors: sharma sk. Eur J Nucl Med Mol Imaging. 2004 Aug;31(8):1090-6. doi: 10.1007/s00259-004-1474-4. Epub 2004 Mar 17. Eur J Nucl Med Mol Imaging. 2004. PMID: 15029458
3,257 results