Lu X - Search Results

1

The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.

Lu X, Ma O, Nguyen TA, Jones SN, Oren M, Donehower LA. Lu X, et al. Cancer Cell. 2007 Oct;12(4):342-54. doi: 10.1016/j.ccr.2007.08.033. Cancer Cell. 2007. PMID: 17936559 Free article.

2

p53 mutant mice that display early ageing-associated phenotypes.

Tyner SD, Venkatachalam S, Choi J, Jones S, Ghebranious N, Igelmann H, Lu X, Soron G, Cooper B, Brayton C, Park SH, Thompson T, Karsenty G, Bradley A, Donehower LA. Tyner SD, et al. Among authors: lu x. Nature. 2002 Jan 3;415(6867):45-53. doi: 10.1038/415045a. Nature. 2002. PMID: 11780111

3

Activities of wildtype and mutant p53 in suppression of homologous recombination as measured by a retroviral vector system.

Lu X, Lozano G, Donehower LA. Lu X, et al. Mutat Res. 2003 Jan 28;522(1-2):69-83. doi: 10.1016/s0027-5107(02)00261-0. Mutat Res. 2003. PMID: 12517413

4

Generation and characterization of p53 mutant mice.

Dumble ML, Donehower LA, Lu X. Dumble ML, et al. Among authors: lu x. Methods Mol Biol. 2003;234:29-49. doi: 10.1385/1-59259-408-5:29. Methods Mol Biol. 2003. PMID: 12824523

5

The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair.

Lu X, Bocangel D, Nannenga B, Yamaguchi H, Appella E, Donehower LA. Lu X, et al. Mol Cell. 2004 Aug 27;15(4):621-34. doi: 10.1016/j.molcel.2004.08.007. Mol Cell. 2004. PMID: 15327777 Free article.

6

Homeostatic regulation of base excision repair by a p53-induced phosphatase: linking stress response pathways with DNA repair proteins.

Lu X, Nguyen TA, Appella E, Donehower LA. Lu X, et al. Cell Cycle. 2004 Nov;3(11):1363-6. doi: 10.4161/cc.3.11.1241. Epub 2004 Nov 15. Cell Cycle. 2004. PMID: 15539943

7

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints.

Lu X, Nannenga B, Donehower LA. Lu X, et al. Genes Dev. 2005 May 15;19(10):1162-74. doi: 10.1101/gad.1291305. Epub 2005 May 3. Genes Dev. 2005. PMID: 15870257 Free PMC article.

8

Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D.

Lu X, Nguyen TA, Donehower LA. Lu X, et al. Cell Cycle. 2005 Aug;4(8):1060-4. Epub 2005 Aug 26. Cell Cycle. 2005. PMID: 15970689

9

53BP1 oligomerization is independent of its methylation by PRMT1.

Adams MM, Wang B, Xia Z, Morales JC, Lu X, Donehower LA, Bochar DA, Elledge SJ, Carpenter PB. Adams MM, et al. Among authors: lu x. Cell Cycle. 2005 Dec;4(12):1854-61. doi: 10.4161/cc.4.12.2282. Epub 2005 Dec 28. Cell Cycle. 2005. PMID: 16294047

10

Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice.

Nannenga B, Lu X, Dumble M, Van Maanen M, Nguyen TA, Sutton R, Kumar TR, Donehower LA. Nannenga B, et al. Among authors: lu x. Mol Carcinog. 2006 Aug;45(8):594-604. doi: 10.1002/mc.20195. Mol Carcinog. 2006. PMID: 16652371

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