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Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656.
Scholz EP, Konrad FM, Weiss DL, Zitron E, Kiesecker C, Bloehs R, Kulzer M, Thomas D, Kathöfer S, Bauer A, Maurer MH, Seemann G, Katus HA, Karle CA. Scholz EP, et al. Among authors: katus ha. Naunyn Schmiedebergs Arch Pharmacol. 2007 Dec;376(4):275-84. doi: 10.1007/s00210-007-0202-6. Epub 2007 Oct 27. Naunyn Schmiedebergs Arch Pharmacol. 2007. PMID: 17965852
Inhibition of cloned HERG potassium channels by the antiestrogen tamoxifen.
Thomas D, Gut B, Karsai S, Wimmer AB, Wu K, Wendt-Nordahl G, Zhang W, Kathöfer S, Schoels W, Katus HA, Kiehn J, Karle CA. Thomas D, et al. Among authors: katus ha. Naunyn Schmiedebergs Arch Pharmacol. 2003 Jul;368(1):41-8. doi: 10.1007/s00210-003-0766-8. Epub 2003 Jun 25. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 12827215
Are electrophysiological studies needed prior to defibrillator implantation?
Becker R, Melkumov M, Senges-Becker JC, Voss F, Bauer A, Michaelsen J, Weretka S, Niroomand F, Katus HA, Schoels W. Becker R, et al. Among authors: katus ha. Pacing Clin Electrophysiol. 2003 Aug;26(8):1715-21. doi: 10.1046/j.1460-9592.2003.t01-1-00257.x. Pacing Clin Electrophysiol. 2003. PMID: 12877705
Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine.
Scholz EP, Zitron E, Kiesecker C, Lueck S, Kathöfer S, Thomas D, Weretka S, Peth S, Kreye VA, Schoels W, Katus HA, Kiehn J, Karle CA. Scholz EP, et al. Among authors: katus ha. Naunyn Schmiedebergs Arch Pharmacol. 2003 Nov;368(5):404-14. doi: 10.1007/s00210-003-0805-5. Epub 2003 Oct 14. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 14557918
1,511 results