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Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656.
Scholz EP, Konrad FM, Weiss DL, Zitron E, Kiesecker C, Bloehs R, Kulzer M, Thomas D, Kathöfer S, Bauer A, Maurer MH, Seemann G, Katus HA, Karle CA. Scholz EP, et al. Among authors: weiss dl. Naunyn Schmiedebergs Arch Pharmacol. 2007 Dec;376(4):275-84. doi: 10.1007/s00210-007-0202-6. Epub 2007 Oct 27. Naunyn Schmiedebergs Arch Pharmacol. 2007. PMID: 17965852
Modeling of IK1 mutations in human left ventricular myocytes and tissue.
Seemann G, Sachse FB, Weiss DL, Ptácek LJ, Tristani-Firouzi M. Seemann G, et al. Among authors: weiss dl. Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H549-59. doi: 10.1152/ajpheart.00701.2006. Epub 2006 Aug 25. Am J Physiol Heart Circ Physiol. 2007. PMID: 16936001 Free article.
83 results